NME1 Antibody / NM23

• Catalog number
  R31976
• Price
  Please ask
• Size
  0.1mg

• Category
  Antibody
• Concentration
  0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  NME1 / NM23
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens), Mouse (Mus musculus), Rat ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB
• Recommended dilutions
  Western blot: 0.1-0.5ug/ml
• Notes
  Optimal dilution of the NM23 antibody should be determined by the researcher.
• Intented use
  This NM23 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  P15531
• Purity
  Antigen affinity
• Description
  NME1, also called NM23, NM23-H1, NDPKA, GAAD or AWD, is an enzyme that in humans is encoded by the NME1 gene. The promoters of the mouse and human NME1 genes, like those of other NME genes, contain several binding sites for AP2, NF1, Sp1, LEF1, and response elements to glucocorticoid receptors. The NME1 gene is mapped on 17q21.33. Immunofluorescence microscopy demonstrated colocalization of NME1 in nuclei of B cells expressing EBNA3C. Expression of EBNA3C reversed the ability of NME1 to inhibit migration of BL and breast carcinoma cells. NM23H1 bound SET and was released from inhibition by GZMA cleavage of SET. After GZMA loading or cytotoxic T lymphocyte attack, SET and NM23H1 translocated to the nucleus and SET was degraded, allowing NM23H1 to nick chromosomal DNA. Using a Drosophila model system, Dammai et al. (2003) showed that the Drosophila NME1 homolog, awd, regulates trachea cell motility by modulating FGFR levels through a dynamin -mediated pathway.
• Immunogen
  Amino acids KRFEQKGFRLVGLKFMQASEDLLKEHYVDLKDR of human NM23A were used as the immunogen for the NM23 antibody.
• Storage
  After reconstitution, the NM23 antibody may be kept for up to one month refrigerated at +4 degrees C.For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  NME1   NM23  
• Gene symbol
  NME1, NME1-NME2, NME3, RMRP, NME5, NME2, RP2, NME4, NME6, NME7
• Short name
  Anti-NME1 / NM23
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibodies to NME1 / NM23
• Alternative technique
  antibodies
• Alternative to gene target
  NME/NM23 nucleoside diphosphate kinase 1, AWD and GAAD and NB and NBS and NDKA and NDPK-A and NDPKA and NM23 and NM23-H1, NME1 and IDBG-409263 and ENSG00000239672 and 4830, poly(A) RNA binding, nuclei, Nme1 and IDBG-208565 and ENSMUSG00000037601 and 18102, NME1 and IDBG-638442 and ENSBTAG00000004651 and 404189

Gene info

• Identity
  HGNC:7849
• Gene
  NME1
• Long gene name
  NME/NM23 nucleoside diphosphate kinase 1
• Synonyms gene name
  • non-metastatic cells 1, protein (NM23A) expressed in
• Synonyms
  • NM23
  • NM23-H1
  • NDPKA
• GenBank acession
  • AL360191
  • X17620
• Locus
  17q21.33
• Discovery year
  1991-07-26
• Entrez gene record
  4830
• Pubmed identfication
  • 8270257
  • 19852809
• RefSeq identity
  • NM_000269
• Classification
  • NME/NM23 family
  • SET complex
• VEGA ID
  OTTHUMG00000137474

Gene info

• Identity
  HGNC:33531
• Gene
  NME1-NME2
• Long gene name
  NME1-NME2 readthrough
• Synonyms
  • NM23-LV
  • NMELV
• GenBank acession
  • DQ109675
• Locus
  17q21.33
• Discovery year
  2007-07-31
• Entrez gene record
  654364
• Pubmed identfication
  • 16442775
• VEGA ID
  OTTHUMG00000137475

Gene info

• Identity
  HGNC:7851
• Gene
  NME3
• Long gene name
  NME/NM23 nucleoside diphosphate kinase 3
• Synonyms gene name
  • non-metastatic cells 3, protein expressed in
• Synonyms
  • DR-nm23
  • NM23-H3
  • NDPKC
• GenBank acession
  • U29656
• Locus
  16p13.3
• Discovery year
  1996-12-19
• Entrez gene record
  4832
• Pubmed identfication
  • 9067290
  • 19852809
• RefSeq identity
  • NM_002513
• Classification
  • NME/NM23 family
• VEGA ID
  OTTHUMG00000128635

Gene info

• Identity
  HGNC:10031
• Gene
  RMRP
• Long gene name
  RNA component of mitochondrial RNA processing endoribonuclease
• Synonyms gene
  • CHH
• Synonyms gene name
  • cartilage-hair hypoplasia
• Synonyms
  • RMRPR
  • RRP2
  • NME1
• GenBank acession
  • M29916
• Locus
  9p13.3
• Discovery year
  1989-06-30
• Entrez gene record
  6023
• Pubmed identfication
  • 11207361
  • 1623519
• RefSeq identity
  • NR_003051
• Locus Specific Databases
  • LRG_163

Gene info

• Identity
  HGNC:7853
• Gene
  NME5
• Long gene name
  NME/NM23 family member 5
• Synonyms gene name
  • non-metastatic cells 5, protein expressed in (nucleoside-diphosphate kinase)
• Synonyms
  • nm23-H5
  • RSPH23
• Synonyms name
  • radial spoke 23 homolog (Chlamydomonas)
• GenBank acession
  • Y14992
• Locus
  5q31.2
• Discovery year
  1998-02-26
• Entrez gene record
  8382
• Pubmed identfication
  • 9742940
  • 19852809
• RefSeq identity
  • NM_003551
• Classification
  • NME/NM23 family
• VEGA ID
  OTTHUMG00000129207

Gene info

• Identity
  HGNC:7850
• Gene
  NME2
• Long gene name
  NME/NM23 nucleoside diphosphate kinase 2
• Synonyms gene name
  • non-metastatic cells 2, protein (NM23B) expressed in
• Synonyms
  • NM23-H2
  • NDPKB
• GenBank acession
  • X58965
• Locus
  17q21.33
• Discovery year
  1991-07-26
• Entrez gene record
  4831
• Pubmed identfication
  • 1988104
  • 19852809
• RefSeq identity
  • NM_002512
• Classification
  • NME/NM23 family
• VEGA ID
  OTTHUMG00000154062

Gene info

• Identity
  HGNC:10274
• Gene
  RP2
• Long gene name
  RP2 activator of ARL3 GTPase
• Synonyms gene name
  • retinitis pigmentosa 2 (X-linked recessive)
  • RP2, ARL3 GTPase activating protein
• Synonyms
  • TBCCD2
  • NME10
  • NM23-H10
• GenBank acession
  • AJ007590
• Locus
  Xp11.3
• Discovery year
  2001-06-22
• Entrez gene record
  6102
• Pubmed identfication
  • 18376416
  • 6325945
  • 9697692
  • 19852809
• RefSeq identity
  • NM_006915
• VEGA ID
  OTTHUMG00000021430
• Locus Specific Databases
  • Mutations of the RP2 Gene
  • Global Variome shared LOVD

Gene info

• Identity
  HGNC:7852
• Gene
  NME4
• Long gene name
  NME/NM23 nucleoside diphosphate kinase 4
• Synonyms gene name
  • non-metastatic cells 4, protein expressed in
• Synonyms
  • nm23-H4
  • NM23H4
  • NDPKD
• GenBank acession
  • Y07604
• Locus
  16p13.3
• Discovery year
  1996-12-19
• Entrez gene record
  4833
• Pubmed identfication
  • 9099850
  • 19852809
• RefSeq identity
  • NM_005009
• Classification
  • NME/NM23 family
• VEGA ID
  OTTHUMG00000047995

Gene info

• Identity
  HGNC:20567
• Gene
  NME6
• Long gene name
  NME/NM23 nucleoside diphosphate kinase 6
• Synonyms gene name
  • non-metastatic cells 6, protein expressed in (nucleoside-diphosphate kinase)
• Synonyms
  • NM23-H6
  • IPIA-ALPHA
• GenBank acession
  • AF051941
• Locus
  3p21.31
• Discovery year
  2003-02-25
• Entrez gene record
  10201
• Pubmed identfication
  • 10453732
  • 19852809
• RefSeq identity
  • NM_005793
• Classification
  • NME/NM23 family
• VEGA ID
  OTTHUMG00000133531

Gene info

• Identity
  HGNC:20461
• Gene
  NME7
• Long gene name
  NME/NM23 family member 7
• Synonyms gene name
  • non-metastatic cells 7, protein expressed in (nucleoside-diphosphate kinase)
• Synonyms
  • FLJ37194
  • NM23-H7
  • CFAP67
• Synonyms name
  • cilia and flagella associated protein 67
• GenBank acession
  • AF153191
• Locus
  1q24.2
• Discovery year
  2003-02-24
• Entrez gene record
  29922
• Pubmed identfication
  • 19852809
• RefSeq identity
  • NM_013330
• Classification
  • NME/NM23 family
  • Cilia and flagella associated
• VEGA ID
  OTTHUMG00000034586

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Similar products