NMDAR2C Antibody / GRIN2C

• Catalog number
  R32230
• Price
  Please ask
• Size
  0.1mg

• Category
  Antibody
• Concentration
  0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  NMDAR2C / GRIN2C
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens), Rat ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB
• Recommended dilutions
  Western blot: 0.1-0.5ug/ml
• Notes
  Optimal dilution of the NMDAR2C antibody should be determined by the researcher.
• Intented use
  This NMDAR2C antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  Q14957
• Purity
  Antigen affinity
• Description
  NMDAR2C, known as GRIN2C, is mapped to 17q25.1. Glutamate [NMDA] receptor subunit epsilon-3 is a protein that in humans is encoded by the GRIN2C gene. NMDA receptors are found in the central nervous system, are permeable to cations and have an important role in physiological processes such as learning, memory, and synaptic development. The receptor is a tetramer of different subunits (typically heterodimer of subunit 1 with one or more of subunits 2A-D), forming a channel that is permeable to calcium, potassium, and sodium, and whose properties are determined by subunit composition. Alterations in the subunit composition of the receptor are associated with pathophysiological conditions such as Parkinson's disease, Alzheimer's disease, depression, and schizophrenia. Alternative splicing results in multiple transcript variants.
• Immunogen
  Amino acids 43-242 of human NMDAR2C were used as the immunogen for the NMDAR2C antibody.
• Storage
  After reconstitution, the NMDAR2C antibody may be kept for up to one month refrigerated at +4 degrees C.For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  NMDAR2C   GRIN2C  
• Gene symbol
  GRIN2C
• Short name
  Anti-NMDAR2C / GRIN2C
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibodies to NMDAR2C / GRIN2C
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:4587
• Gene
  GRIN2C
• Long gene name
  glutamate ionotropic receptor NMDA type subunit 2C
• Synonyms gene
  • NMDAR2C
• Synonyms gene name
  • glutamate receptor, ionotropic, N-methyl D-aspartate 2C
• Synonyms
  • GluN2C
• Locus
  17q25.1
• Discovery year
  1992-09-18
• Entrez gene record
  2905
• Pubmed identfication
  • 9480759
• Classification
  • Glutamate ionotropic receptor NMDA type subunits
• VEGA ID
  OTTHUMG00000044524

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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