NFATC1 Antibody

• Catalog number
  F43345-0.08ML
• Price
  Please ask
• Size
  0.08 ml

• Category
  Antibody
• Concentration
  In 1X PBS, pH 7.4, with 0.09% sodium azide
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  NFATC1
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, IHC, ELISA
• Recommended dilutions
  Western blot: 1:1000,IHC (Paraffin): 1:10-1:50
• Notes
  Titration of the NFATC1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This NFATC1 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  O95644
• Purity
  Antigen affinity
• Description
  The product of this gene is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. The product of this gene is an inducible nuclear component. It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Five transcript variants encoding distinct isoforms have been identified for this gene. Different isoforms of this protein may regulate inducible expression of different cytokine genes.
• Immunogen
  A portion of amino acids 898-927 from the human protein was used as the immunogen for this NFATC1 antibody.
• Storage
  Aliquot the NFATC1 antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  NFATC1  
• Gene symbol
  NFATC1
• Short name
  Anti-NFATC1
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit Ig
• Alternative name
  Antibodies to NFATC1
• Alternative technique
  antibodies
• Alternative to gene target
  nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1, NF-ATC and NFAT2 and NFATc, NFATC1 and IDBG-5452 and ENSG00000131196 and 4772, mitogen-activated protein kinase p38 binding, nuclei, Nfatc1 and IDBG-161489 and ENSMUSG00000033016 and 18018, NFATC1 and IDBG-643394 and ENSBTAG00000000656 and 511224

Gene info

• Identity
  HGNC:7775
• Gene
  NFATC1
• Long gene name
  nuclear factor of activated T cells 1
• Synonyms gene name
  • nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
  • nuclear factor of activated T-cells 1
• Synonyms
  • NF-ATC
  • NFATc
  • NFAT2
• GenBank acession
  • U08015
• Locus
  18q23
• Discovery year
  1994-11-16
• Entrez gene record
  4772
• Pubmed identfication
  • 8202141
• RefSeq identity
  • NM_172390
• Classification
  • Nuclear factors of activated T-cells
  • IPT domain containing
• VEGA ID
  OTTHUMG00000132897

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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