MyD88 Antibody
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Catalog numberF51176-0.4ML
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PricePlease ask
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Size0.4 ml
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CategoryAntibody
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ConcentrationIn 1X PBS, pH 7.4, with 0.09% sodium azide
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FormAntigen affinity purified
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ConjugationUnconjugated
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ClonePolyclonal antibody
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Recognised antigenMyD88
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Host animalRabbit (Oryctolagus cuniculus)
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ClonalityPolyclonal (rabbit origin)
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Species reactivityHuman (Homo sapiens), Mouse (Mus musculus) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
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Tested applicationsWB, IHC, FACS, ELISA
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Recommended dilutionsWestern blot: 1:1000,IHC (Paraffin): 1:10-1:50,Flow Cytometry: 1:10-1:50
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NotesTitration of the MyD88 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Intented useThis MyD88 antibodyis to be used only for research purposes and not for diagnostics..
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UniprotQ99836
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PurityAntigen affinity
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DescriptionAdapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. It acts via IRAK1, IRAK2 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response and increases IL-8 transcription. It may be involved in myeloid differentiation.
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ImmunogenA portion of amino acids 136-164 from the human protein was used as the immunogen for this MyD88 antibody.
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StorageAliquot the MyD88 antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
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PropertiesIf you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolMYD88, TIRAP, MAL
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Short nameAnti-MyD88
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TechniqueAntibody, antibodies against human proteins, antibodies for
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IsotypeRabbit Ig
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Alternative nameAntibodies to MyD88
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Alternative techniqueantibodies
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Alternative to gene targetmyeloid differentiation primary response 88, MYD88D, MYD88 and IDBG-25713 and ENSG00000172936 and 4615, TIR domain binding, Plasma membranes, Myd88 and IDBG-204565 and ENSMUSG00000032508 and 17874, MYD88 and IDBG-644299 and ENSBTAG00000000563 and 444881
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Gene info
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Identity
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Gene
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Long gene nameMYD88 innate immune signal transduction adaptor
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Synonyms gene name
- myeloid differentiation primary response gene (88)
- myeloid differentiation primary response 88
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GenBank acession
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Locus
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Discovery year1997-12-23
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- TIR domain containing
- My-T-BRC complex
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nameTIR domain containing adaptor protein
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Synonyms gene name
- Toll-interleukin 1 receptor (TIR) domain-containing adaptor protein
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2003-06-05
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- TIR domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namemal, T cell differentiation protein
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Synonyms gene name
- mal, T-cell differentiation protein
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Synonyms
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Synonyms name
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Locus
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Discovery year1986-01-01
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- MARVEL domain containing
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data