MRP8 Antibody / ABCC11

• Catalog number
  F48871-0.08ML
• Price
  Please ask
• Size
  0.08 ml

• Category
  Antibody
• Concentration
  In 1X PBS, pH 7.4, with 0.09% sodium azide
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  MRP8 / ABCC11
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, IHC, ELISA
• Recommended dilutions
  Western blot: 1:1000,IHC (Paraffin): 1:50-1:100
• Intented use
  This ABCC11 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  Q96J66
• Purity
  Antigen affinity
• Description
  ATP-binding cassette sub-family C member 11 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This ABC full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. The product of this gene participates in physiological processes involving bile acids, conjugated steroids, and cyclic nucleotides. In addition, a SNP in this gene is responsible for determination of human earwax type. This gene and family member ABCC12 are determined to be derived by duplication and are both localized to chromosome 16q12.1.
• Immunogen
  A portion of amino acids 343-372 from the human protein was used as the immunogen for this ABCC11 antibody.
• Storage
  Aliquot the ABCC11 antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
• Localization
  Cytoplasmic, membranous
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  MRP8   ABCC11  
• Gene symbol
  ABCC11, ABCC8, S100A8
• Short name
  Anti- MRP8 / ABCC11
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit Ig
• Alternative name
  Antibodies to MRP8 / ABCC11
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:14639
• Gene
  ABCC11
• Long gene name
  ATP binding cassette subfamily C member 11
• Synonyms gene name
  • ATP-binding cassette, sub-family C (CFTR/MRP), member 11
• Synonyms
  • MRP8
• GenBank acession
  • AF367202
• Locus
  16q12.1
• Discovery year
  2001-06-01
• Entrez gene record
  85320
• Pubmed identfication
  • 11483364
  • 11435397
• RefSeq identity
  • NM_032583
• Classification
  • ATP binding cassette subfamily C
• VEGA ID
  OTTHUMG00000133146

Gene info

• Identity
  HGNC:59
• Gene
  ABCC8
• Long gene name
  ATP binding cassette subfamily C member 8
• Synonyms gene
  • SUR
  • HRINS
• Synonyms gene name
  • ATP-binding cassette, sub-family C (CFTR/MRP), member 8
• Synonyms
  • HI
  • PHHI
  • SUR1
  • MRP8
  • ABC36
  • HHF1
  • TNDM2
• Synonyms name
  • sulfonylurea receptor (hyperinsulinemia)
• GenBank acession
  • L78207
• Locus
  11p15.1
• Discovery year
  1995-01-10
• Entrez gene record
  6833
• Pubmed identfication
  • 7920639
  • 7716548
• RefSeq identity
  • NM_000352
• Classification
  • ATP binding cassette subfamily C
• VEGA ID
  OTTHUMG00000166316
• Locus Specific Databases
  • LRG_790

Gene info

• Identity
  HGNC:10498
• Gene
  S100A8
• Long gene name
  S100 calcium binding protein A8
• Synonyms gene
  • CAGA
  • CFAG
• Synonyms gene name
  • calgranulin A
  • cystic fibrosis antigen
• Synonyms
  • P8
  • MRP8
  • MRP-8
  • 60B8AG
  • CGLA
  • S100-A8
• Synonyms name
  • Migration inhibitory factor-related protein 8
  • Calprotectin L1L subunit
  • Leukocyte L1 complex light chain
• GenBank acession
  • BC005928
• Locus
  1q21.3
• Discovery year
  1989-05-19
• Entrez gene record
  6279
• RefSeq identity
  • NM_002964
• Classification
  • S100 calcium binding proteins
  • EF-hand domain containing
• VEGA ID
  OTTHUMG00000013124

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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