MMP3 Antibody

  • Catalog number
    F43043-0.08ML
  • Price
    Please ask
  • Size
    0.08 ml
  • Category
    Antibody
  • Concentration
    In 1X PBS, pH 7.4, with 0.09% sodium azide
  • Form
    Antigen affinity purified
  • Conjugation
    Unconjugated
  • Clone
    Polyclonal antibody
  • Recognised antigen
    MMP3
  • Host animal
    Rabbit (Oryctolagus cuniculus)
  • Clonality
    Polyclonal (rabbit origin)
  • Species reactivity
    Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
  • Tested applications
    IHC, IF, WB, ELISA
  • Recommended dilutions
    Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Immunofluorescence: 1:10-1:50
  • Notes
    Titration of the MMP3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
  • Intented use
    This MMP3 antibodyis to be used only for research purposes and not for diagnostics..
  • Uniprot
    P08254
  • Purity
    Antigen affinity
  • Description
    Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.
  • Immunogen
    A portion of amino acids 30-59 from the human protein was used as the immunogen for this MMP3 antibody.
  • Storage
    Aliquot the MMP3 antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
  • Properties
    If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • French translation
    anticorps
  • Gene target
    MMP3  
  • Gene symbol
    MMP3
  • Short name
    Anti-MMP3
  • Technique
    Antibody, antibodies against human proteins, antibodies for
  • Isotype
    Rabbit Ig
  • Alternative name
    Antibodies to MMP3
  • Alternative technique
    antibodies
  • Alternative to gene target
    matrix metallopeptidase 3 (stromelysin 1, progelatinase), CHDS6 and MMP-3 and SL-1 and STMY and STMY1 and STR1, MMP3 and IDBG-69254 and ENSG00000149968 and 4314, zinc ion binding, Extracellular, Mmp3 and IDBG-132579 and ENSMUSG00000043613 and 17392, BT.18504 and IDBG-629038 and ENSBTAG00000037768 and 100848277
Gene info
  • Identity
  • Gene
  • Long gene name
    matrix metallopeptidase 3
  • Synonyms gene
  • Synonyms gene name
    • matrix metalloproteinase 3 (stromelysin 1, progelatinase)
    • stromelysin 1
  • GenBank acession
  • Locus
  • Discovery year
    2001-06-22
  • Entrez gene record
  • RefSeq identity
  • Classification
    • M10 matrix metallopeptidases
  • VEGA ID
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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