MMP3 Antibody
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Catalog numberF43043-0.08ML
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PricePlease ask
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Size0.08 ml
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CategoryAntibody
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ConcentrationIn 1X PBS, pH 7.4, with 0.09% sodium azide
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FormAntigen affinity purified
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ConjugationUnconjugated
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ClonePolyclonal antibody
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Recognised antigenMMP3
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Host animalRabbit (Oryctolagus cuniculus)
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ClonalityPolyclonal (rabbit origin)
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Species reactivityHuman (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
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Tested applicationsIHC, IF, WB, ELISA
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Recommended dilutionsWestern blot: 1:1000,IHC (Paraffin): 1:10-1:50,Immunofluorescence: 1:10-1:50
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NotesTitration of the MMP3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Intented useThis MMP3 antibodyis to be used only for research purposes and not for diagnostics..
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UniprotP08254
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PurityAntigen affinity
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DescriptionProteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.
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ImmunogenA portion of amino acids 30-59 from the human protein was used as the immunogen for this MMP3 antibody.
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StorageAliquot the MMP3 antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
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PropertiesIf you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolMMP3
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Short nameAnti-MMP3
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TechniqueAntibody, antibodies against human proteins, antibodies for
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IsotypeRabbit Ig
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Alternative nameAntibodies to MMP3
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Alternative techniqueantibodies
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Alternative to gene targetmatrix metallopeptidase 3 (stromelysin 1, progelatinase), CHDS6 and MMP-3 and SL-1 and STMY and STMY1 and STR1, MMP3 and IDBG-69254 and ENSG00000149968 and 4314, zinc ion binding, Extracellular, Mmp3 and IDBG-132579 and ENSMUSG00000043613 and 17392, BT.18504 and IDBG-629038 and ENSBTAG00000037768 and 100848277
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Gene info
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Identity
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Gene
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Long gene namematrix metallopeptidase 3
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Synonyms gene
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Synonyms gene name
- matrix metalloproteinase 3 (stromelysin 1, progelatinase)
- stromelysin 1
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GenBank acession
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Locus
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Discovery year2001-06-22
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Entrez gene record
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RefSeq identity
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Classification
- M10 matrix metallopeptidases
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data