MMP1 Antibody

• Catalog number
  R31876
• Price
  Please ask
• Size
  0.1mg

• Category
  Antibody
• Concentration
  0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  MMP1
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB
• Recommended dilutions
  Western blot: 0.1-0.5ug/ml
• Notes
  Optimal dilution of the MMP-1 antibody should be determined by the researcher.
• Intented use
  This MMP-1 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  P03956
• Purity
  Antigen affinity
• Description
  Matrix metalloproteinase-1 (MMP-1), also known as interstitial collagenase and fibroblast collagenase, is an enzyme that in humans is encoded by the MMP1 gene. MMP-1 was the first vertebrate collagenase both purified to homogeneity as a protein, and cloned as a cDNA. Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes a secreted enzyme which breaks down the interstitial collagens, types I, II, and III. It is part of a cluster of MMP genes which localize to chromosome 11q22.3. Alternative splicing results in multiple transcript variants.
• Immunogen
  Amino acids DAHFDEDERWTNNFREYNLHRVAAHELGHSLGLSHSTD of human MMP1 were used as the immunogen for the MMP-1 antibody.
• Storage
  After reconstitution, the MMP-1 antibody may be kept for up to one month refrigerated at +4 degrees C.For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  MMP1  
• Gene symbol
  MMP1
• Short name
  Anti-MMP1
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibodies to MMP1
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:7155
• Gene
  MMP1
• Long gene name
  matrix metallopeptidase 1
• Synonyms gene
  • CLG
• Synonyms gene name
  • matrix metalloproteinase 1 (interstitial collagenase)
• Synonyms name
  • interstitial collagenase
• GenBank acession
  • X54925
• Locus
  11q22.2
• Discovery year
  1986-01-01
• Entrez gene record
  4312
• RefSeq identity
  • NM_002421
• Classification
  • M10 matrix metallopeptidases
  • Receptor ligands
• VEGA ID
  OTTHUMG00000048192

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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