MARK2 Antibody

• Catalog number
  F40167-0.4ML
• Price
  Please ask
• Size
  0.4 ml

• Category
  Antibody
• Concentration
  In 1X PBS, pH 7.4, with 0.09% sodium azide
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  MARK2
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens), Mouse (Mus musculus) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, IHC, ELISA
• Recommended dilutions
  Western blot: 1:1000,IHC (Paraffin): 1:50-1:100
• Notes
  Titration of the MARK2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This MARK2 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  Q7KZI7
• Purity
  Antigen affinity
• Description
  Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.
• Immunogen
  A portion of amino acids 600-630 from the human protein was used as the immunogen for this MARK2 antibody.
• Storage
  Aliquot the MARK2 antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  MARK2  
• Gene symbol
  MARK2
• Short name
  Anti-MARK2
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit Ig
• Alternative name
  Antibodies to MARK2
• Alternative technique
  antibodies
• Alternative to gene target
  MAP/microtubule affinity-regulating kinase 2, EMK-1 and EMK1 and PAR-1 and Par-1b and Par1b, MARK2 and IDBG-52754 and ENSG00000072518 and 2011, transferase activity, nuclei, Mark2 and IDBG-138576 and ENSMUSG00000024969 and 13728, MARK2 and IDBG-643848 and ENSBTAG00000007825 and 535197

Gene info

• Identity
  HGNC:3332
• Gene
  MARK2
• Long gene name
  microtubule affinity regulating kinase 2
• Synonyms gene
  • EMK1
• Synonyms gene name
  • ELKL motif kinase
  • MAP/microtubule affinity-regulating kinase 2
• Synonyms
  • PAR-1
  • Par1b
  • PAR-1B
• Synonyms name
  • ELKL motif kinase 1
  • serine/threonine kinase
  • protein-serine/threonine kinase
  • Ser/Thr protein kinase PAR-1B
• GenBank acession
  • BC008771
• Locus
  11q13.1
• Discovery year
  1994-12-08
• Entrez gene record
  2011
• Pubmed identfication
  • 9730619
  • 10516437
• RefSeq identity
  • NM_017490
• VEGA ID
  OTTHUMG00000160504

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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