MAPK11 Antibody

• Catalog number
  F40153-0.4ML
• Price
  Please ask
• Size
  0.4 ml

• Category
  Antibody
• Concentration
  In 1X PBS, pH 7.4, with 0.09% sodium azide
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  MAPK11
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens), Mouse (Mus musculus) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, ELISA
• Recommended dilutions
  Western blot: 1:1000
• Notes
  Titration of the MAPK11 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This MAPK11 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  Q15759
• Purity
  Antigen affinity
• Description
  P38 beta is a member of the MAP kinase subfamily of Ser/Thr protein kinases. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is closely related to p38 MAP kinase, both of which can be activated by changes in osmolarity of the extracellular environment, proinflammatory cytokines and cellular stress. This protein preferentially phosphorylates transcription factor ATF2. It is activated by phosphorylation on threonine and tyrosine by MKK6, and inhibited by pyridinyl-imidazole related compounds. Highest levels of expression are found in the brain and heart, with additional expression in the placenta, lung, liver, skeletal muscle, kidney and pancreas.
• Immunogen
  A portion of amino acids 133-161 from the human protein was used as the immunogen for this MAPK11 antibody.
• Storage
  Aliquot the MAPK11 antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  MAPK11  
• Gene symbol
  MAPK11
• Short name
  Anti-MAPK11
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit Ig
• Alternative name
  Antibodies to MAPK11
• Alternative technique
  antibodies
• Alternative to gene target
  mitogen-activated protein kinase 11, p38-2 and P38B and p38Beta and P38BETA2 and PRKM11 and SAPK2 and SAPK2B, MAPK11 and IDBG-13123 and ENSG00000185386 and 5600, transferase activity, nuclei, Mapk11 and IDBG-172712 and ENSMUSG00000053137 and 19094, MAPK11 and IDBG-642533 and ENSBTAG00000030182 and 618906

Gene info

• Identity
  HGNC:6873
• Gene
  MAPK11
• Long gene name
  mitogen-activated protein kinase 11
• Synonyms gene
  • PRKM11
• Synonyms
  • p38-2
  • p38Beta
  • SAPK2
• GenBank acession
  • Y14440
• Locus
  22q13.33
• Discovery year
  1998-04-28
• Entrez gene record
  5600
• Pubmed identfication
  • 9218798
• Classification
  • Mitogen-activated protein kinases
• VEGA ID
  OTTHUMG00000150226

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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