Lipoprotein lipase Antibody

• Catalog number
  R30361
• Price
  Please ask
• Size
  0.1mg

• Category
  Antibody
• Concentration
  0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  Lipoprotein lipase
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens), Mouse (Mus musculus), Rat, Bovine ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB
• Recommended dilutions
  Western blot: 0.5-1ug/ml
• Notes
  The stated application concentrations are suggested starting amounts. Titration of the Lipoprotein lipase antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This Lipoprotein lipase antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  P06858
• Purity
  Antigen affinity
• Description
  Lipoprotein lipase(LPL) is the central enzyme in plasma triglyceride hydrolysis and is secreted by macrophages in the subendothelial space. Evidence has been provided that LPL produced by macrophages in the vessel wall exerts proatherogenic effects. Lipoprotein lipase has been difficult to purify, and its protein sequence remained undetermined until it could be deduced from the nucleotide sequence of its cDNA. The gene encodes a protein of 475 amino acids that becomes a mature protein of 448 residues after cleavage of a signal peptide. Analysis of the sequence indicated that human lipoprotein lipase, hepatic lipase, and pancreatic lipase are members of a gene family. The atherogenic effects of LPL have been mainly attributed to its ability to favor lipid accumulation within macrophages present in the atherosclerotic lesion.
• Immunogen
  An amino acid sequence from the C-terminus of human Lipoprotein lipase (EKVSHLQKGKAPAVFVKCHDKSL) was used as the immunogen for this Lipoprotein lipase antibody.
• Storage
  After reconstitution, the Lipoprotein lipase antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Lipoprotein   lipase  
• Gene symbol
  LPL
• Short name
  Anti-Lipoprotein lipase
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibodies to Lipoprotein lipase
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:6677
• Gene
  LPL
• Long gene name
  lipoprotein lipase
• Synonyms gene
  • LIPD
• Locus
  8p21.3
• Discovery year
  2001-06-22
• Entrez gene record
  4023
• Pubmed identfication
  • 3823907
  • 3597382
  • 3692485
• Classification
  • Lipases
• VEGA ID
  OTTHUMG00000036645
• Locus Specific Databases
  • LRG_1298

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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