LIM Kinase 1 Antibody / LIMK1
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Catalog number
R32135
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Price
Please ask
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Size
0.1mg
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Category
Antibody
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Concentration
0.5mg/ml if reconstituted with 0.2ml sterile DI water
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Form
Antigen affinity purified
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Conjugation
Unconjugated
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Clone
Polyclonal antibody
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Recognised antigen
LIM Kinase 1 / LIMK1
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Host animal
Rabbit (Oryctolagus cuniculus)
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Clonality
Polyclonal (rabbit origin)
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Species reactivity
Human (Homo sapiens), Mouse (Mus musculus), Rat ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
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Tested applications
WB
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Recommended dilutions
Western blot: 0.1-0.5ug/ml,ELISA : 0.1-0.5ug/ml
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Notes
Optimal dilution of the LIMK antibody should be determined by the researcher.
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Intented use
This LIMK antibodyis to be used only for research purposes and not for diagnostics..
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Uniprot
P53667
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Purity
Antigen affinity
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Description
LIM domain kinase 1 is an enzyme that in humans is encoded by the LIMK1 gene. There are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine-rich structures containing 2 zinc fingers. Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein-protein interactions. LIM kinase-1 and LIM kinase-2 belong to a small subfamily with a unique combination of 2 N-terminal LIM motifs, a central PDZ domain, and a C-terminal protein kinase domain. LIMK1 is likely to be a component of an intracellular signaling pathway and may be involved in brain development.
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Immunogen
Amino acids KLEHWLETLRMHLAGHLPLGPQLEQLDRGFWETYRR of human LIMK1 were used as the immunogen for the LIMK antibody.
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Storage
After reconstitution, the LIMK antibody may be kept for up to one month refrigerated at +4 degrees C.For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
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Properties
If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translation
anticorps
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Gene target
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Gene symbol
LIMK1, PDLIM5, LHX1
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Short name
Anti-LIM Kinase 1 / LIMK1
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Technique
Antibody, antibodies against human proteins, antibodies for
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Isotype
Rabbit IgG
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Alternative name
Antibodies to LIM Kinase 1 / LIMK1
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Alternative technique
antibodies
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Gene info
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Identity
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Gene
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Long gene name
LIM domain kinase 1
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Synonyms
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GenBank acession
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Locus
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Discovery year
1996-03-14
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- LIM domain containing
- PDZ domain containing
- LIMK/TESK kinase family
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
PDZ and LIM domain 5
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Synonyms
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GenBank acession
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Locus
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Discovery year
2005-01-12
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Entrez gene record
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Pubmed identfication
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Classification
- PDZ domain containing
- LIM domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
LIM homeobox 1
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Synonyms
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GenBank acession
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Locus
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Discovery year
1996-10-02
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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