Leupaxin Antibody

• Catalog number
  R31317
• Price
  Please ask
• Size
  0.1mg

• Category
  Antibody
• Concentration
  0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  Leupaxin
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens), Mouse (Mus musculus), Rat ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, IHC-P
• Recommended dilutions
  Western blot: 0.5-1ug/ml,IHC (Paraffin): 0.5-1ug/ml
• Notes
  The stated application concentrations are suggested starting amounts. Titration of the Leupaxin antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This Leupaxin antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  O60711
• Purity
  Antigen affinity
• Description
  Leupaxin is a protein that in humans is encoded by the LPXN gene. This gene is mapped to 11q12.1. The product encoded by this gene is preferentially expressed in hematopoietic cells and belongs to the paxillin protein family. Similar to other members of this focal-adhesion-associated adaptor-protein family, it has four leucine-rich LD-motifs in the N-terminus and four LIM domains in the C-terminus. It may function in cell type-specific signaling by associating with PYK2, a member of focal adhesion kinase family. As a substrate for a tyrosine kinase in lymphoid cells, Leupaxin may also function in, and be regulated by, tyrosine kinase activity.
• Immunogen
  An amino acid sequence from the N-terminus of human Leupaxin (KKHLPDKQDHKASLD) was used as the immunogen for this Leupaxin antibody.
• Storage
  After reconstitution, the Leupaxin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Leupaxin  
• Gene symbol
  LPXN
• Short name
  Anti-Leupaxin
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibodies to Leupaxin
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:14061
• Gene
  LPXN
• Long gene name
  leupaxin
• Synonyms
  • LDPL
• GenBank acession
  • AF062075
• Locus
  11q12.1
• Discovery year
  2000-11-28
• Entrez gene record
  9404
• Pubmed identfication
  • 9565592
• RefSeq identity
  • NM_004811
• Classification
  • LIM domain containing
• VEGA ID
  OTTHUMG00000167466

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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