LDLR Antibody
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Catalog numberF51451-0.08ML
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PricePlease ask
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Size0.08 ml
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CategoryAntibody
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ConcentrationIn 1X PBS, pH 7.4, with 0.09% sodium azide
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FormAntigen affinity purified
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ConjugationUnconjugated
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ClonePolyclonal antibody
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Recognised antigenLDLR
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Host animalRabbit (Oryctolagus cuniculus)
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ClonalityPolyclonal (rabbit origin)
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Species reactivityHuman (Homo sapiens), Mouse (Mus musculus) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
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Tested applicationsWB, FACS, ELISA
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Recommended dilutionsWestern blot: 1:1000,Flow Cytometry: 1:10-1:50
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NotesTitration of the LDLR antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Intented useThis LDLR antibodyis to be used only for research purposes and not for diagnostics..
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UniprotP01130
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PurityAntigen affinity
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DescriptionThe low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place.
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ImmunogenA portion of amino acids 391-419 from the human protein was used as the immunogen for this LDLR antibody.
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StorageAliquot the LDLR antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
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PropertiesIf you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolLDLR, LDLR-AS1
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Short nameAnti-LDLR
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TechniqueAntibody, antibodies against human proteins, antibodies for
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IsotypeRabbit Ig
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Alternative nameAntibodies to LDLR
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Alternative techniqueantibodies
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Alternative to gene targetlow density lipoprotein receptor, FH and FHC and LDLCQ2, LDLR and IDBG-28808 and ENSG00000130164 and 3949, very-low-density lipoprotein particle receptor activity, Cell surfaces, Ldlr and IDBG-141358 and ENSMUSG00000032193 and 16835, LDLR and IDBG-643476 and ENSBTAG00000012314 and 281276
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Gene info
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Identity
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Gene
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Long gene namelow density lipoprotein receptor
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1986-01-01
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Entrez gene record
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Classification
- Low density lipoprotein receptors
- MicroRNA protein coding host genes
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nameLDLR antisense RNA 1
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Synonyms
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Locus
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Discovery year2019-08-08
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Antisense RNAs
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data