KLF4 Antibody

• Catalog number
  F52999-0.08ML
• Price
  Please ask
• Size
  0.08 ml

• Category
  Antibody
• Concentration
  In 1X PBS, pH 7.4, with 0.09% sodium azide
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  KLF4
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, ELISA
• Recommended dilutions
  Western blot: 1:1000
• Notes
  Titration of the KLF4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This KLF4 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  O43474
• Purity
  Antigen affinity
• Description
  Transcription factor; can act both as activator and as repressor. Binds the 5'-CACCC-3' core sequence. Binds to the promoter region of its own gene and can activate its own transcription. Regulates the expression of key transcription factors during embryonic development. Plays an important role in maintaining embryonic stem cells, and in preventing their differentiation. Required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface. Involved in the differentiation of epithelial cells and may also function in skeletal and kidney development. Contributes to the down-regulation of p53/TP53 transcription.
• Immunogen
  This KLF4 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 408-450 amino acids from the C-terminal region of human KLF4.
• Storage
  Aliquot the KLF4 antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  KLF4  
• Gene symbol
  KLF4
• Short name
  Anti-KLF4
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit Ig
• Alternative name
  Antibodies to KLF4
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:6348
• Gene
  KLF4
• Long gene name
  Kruppel like factor 4
• Synonyms gene name
  • Kruppel-like factor 4 (gut)
• Synonyms
  • EZF
  • GKLF
• Synonyms name
  • gut Kruppel-like factor
• GenBank acession
  • AF022184
• Locus
  9q31.2
• Discovery year
  1999-12-14
• Entrez gene record
  9314
• Pubmed identfication
  • 9422764
  • 16372018
• RefSeq identity
  • NM_004235
• Classification
  • Zinc fingers C2H2-type
  • Kruppel like factors
• VEGA ID
  OTTHUMG00000020449

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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