Kdm6b Antibody

• Catalog number
  F52856-0.4ML
• Price
  Please ask
• Size
  0.4 ml

• Category
  Antibody
• Concentration
  In 1X PBS, pH 7.4, with 0.09% sodium azide
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  Kdm6b
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens), Mouse (Mus musculus) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, ELISA
• Recommended dilutions
  Western blot: 1:1000
• Notes
  Titration of the Kdm6b antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This Kdm6b antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  Q5NCY0
• Purity
  Antigen affinity
• Description
  Histone demethylase that specifically demethylates 'Lys- 27' of histone H3, thereby playing a central role in histone code. Demethylates trimethylated and dimethylated H3 'Lys-27'. Plays a central role in regulation of posterior development, by regulating HOX gene expression. Involved in inflammatory response by participating in macrophage differentiation in case of inflammation by regulating gene expression and macrophage differentiation.
• Immunogen
  This Kdm6b antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 1023-1057 amino acids from mouse Kdm6b.
• Storage
  Aliquot the Kdm6b antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Kdm6b  
• Gene symbol
  KDM6B
• Short name
  Anti-Kdm6b
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit Ig
• Alternative name
  Antibodies to Kdm6b
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:29012
• Gene
  KDM6B
• Long gene name
  lysine demethylase 6B
• Synonyms gene
  • JMJD3
• Synonyms gene name
  • jumonji domain containing 3
  • jumonji domain containing 3, histone lysine demethylase
  • lysine (K)-specific demethylase 6B
• Synonyms
  • KIAA0346
• GenBank acession
  • AB002344
• Locus
  17p13.1
• Discovery year
  2004-02-27
• Entrez gene record
  23135
• Pubmed identfication
  • 10662545
  • 9205841
• RefSeq identity
  • NM_001080424
• Classification
  • Lysine demethylases
• VEGA ID
  OTTHUMG00000178021

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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