Kallikrein 10 Antibody

• Catalog number
  R30919
• Price
  Please ask
• Size
  0.1mg

• Category
  Antibody
• Concentration
  0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  Kallikrein 10
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB
• Recommended dilutions
  Western blot: 0.5-1ug/ml
• Notes
  The stated application concentrations are suggested starting amounts. Titration of the Kallikrein 10 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This Kallikrein 10 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  O43240
• Purity
  Antigen affinity
• Description
  Kallikrein-related peptidase 10, also known as KLK10, PRSSL1 or NES1, belongs to the kallikrein subfamily of serine proteases, which are involved in a variety of enzymatic processes. Its encoded protein is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers. KLK10 contains 12 conserved cysteines in its protease domain that are expected to form 6 disulfide bonds, as in other serine proteases. RT-PCR detected variable levels of KLK10 expression in nearly all of the 35 adult and fetal tissues examined. The gene contains 6 exons, the first of which is noncoding. By fluorescence in situ hybridization, Polikoff et al.(1997) mapped the gene to 19q13.3. By genomic sequence analysis,Gan et al.(2000) mapped the gene within the KLK gene cluster on chromosome 19q13. This cluster includes 13 KLK genes and 5 pseudogenes.
• Immunogen
  An amino acid sequence from the C-terminus of human Kallikrein 10 (SAQHPAVYTQICKY) was used as the immunogen for this Kallikrein 10 antibody.
• Storage
  After reconstitution, the Kallikrein 10 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Kallikrein  
• Gene symbol
  KLK10
• Short name
  Anti-Kallikrein 10
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibodies to Kallikrein 10
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:6358
• Gene
  KLK10
• Long gene name
  kallikrein related peptidase 10
• Synonyms gene
  • PRSSL1
• Synonyms gene name
  • kallikrein 10
• Synonyms
  • NES1
• GenBank acession
  • AF024605
• Locus
  19q13.41
• Discovery year
  1997-05-09
• Entrez gene record
  5655
• Pubmed identfication
  • 8764136
  • 9533035
  • 16800724
  • 16800723
  • 10675891
• RefSeq identity
  • NM_002776
• Classification
  • Kallikreins
• VEGA ID
  OTTHUMG00000182916

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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