JNK3 Antibody

• Catalog number
  F50466-0.4ML
• Price
  Please ask
• Size
  0.4 ml

• Category
  Antibody
• Concentration
  In 1X PBS, pH 7.4, with 0.09% sodium azide
• Form
  Purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  JNK3
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens), Mouse (Mus musculus) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, IHC, ELISA
• Recommended dilutions
  Western blot: 1:1000,IHC (Paraffin): 1:50-1:100
• Notes
  Titration of the JNK3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This JNK3 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  P53779
• Purity
  Purified
• Description
  JNK3 is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This protein is a neuronal-specific form of c-Jun N-terminal kinases (JNKs). Through its phosphorylation and nuclear localization, this kinase plays regulatory roles in the signaling pathways during neuronal apoptosis. Beta-arrestin 2, a receptor-regulated MAP kinase scaffold protein, is found to interact with, and stimulate the phosphorylation of this kinase by MAP kinase kinase 4 (MKK4). Cyclin-dependent kinase 5 can phosphorylate and inhibit the activity of this kinase, which may be important in preventing neuronal apoptosis.
• Immunogen
  A portion of amino acids 1-30 from the human protein was used as the immunogen for this JNK3 antibody.
• Storage
  Aliquot the JNK3 antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  JNK3  
• Gene symbol
  MAPK10
• Short name
  Anti-JNK3
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit Ig
• Alternative name
  Antibodies to JNK3
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:6872
• Gene
  MAPK10
• Long gene name
  mitogen-activated protein kinase 10
• Synonyms gene
  • PRKM10
• Synonyms
  • JNK3
  • p493F12
  • p54bSAPK
• GenBank acession
  • U07620
• Locus
  4q21.3
• Discovery year
  1998-04-28
• Entrez gene record
  5602
• Pubmed identfication
  • 8654373
  • 12436199
• Classification
  • Mitogen-activated protein kinases
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000130604

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Similar products