Irak1 Antibody

• Catalog number
  F43845-0.08ML
• Price
  Please ask
• Size
  0.08 ml

• Category
  Antibody
• Concentration
  In 1X PBS, pH 7.4, with 0.09% sodium azide
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  Irak1
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Mouse (Mus musculus) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, FACS, ELISA
• Recommended dilutions
  Western blot: 1:1000,Flow Cytometry: 1:10-1:50
• Notes
  Titration of the Irak1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This Irak1 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  Q62406
• Purity
  Antigen affinity
• Description
  Irak1 binds to the IL-1 type I receptor following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization. The kinase activity of this enzyme may not be required for IL-1 signaling. Once phosphorylated, IRAK1 recruits the adapter protein PELI1.
• Immunogen
  A portion of amino acids 405-433 from the mouse protein was used as the immunogen for this Irak1 antibody.
• Storage
  Aliquot the Irak1 antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Irak1  
• Gene symbol
  IRAK1
• Short name
  Anti-Irak1
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit Ig
• Alternative name
  Antibodies to Irak1
• Alternative technique
  antibodies
• Alternative to gene target
  interleukin-1 receptor-associated kinase 1, IRAK and pelle, IRAK1 and IDBG-90782 and ENSG00000184216 and 3654, transferase activity, nuclei, Irak1 and IDBG-154747 and ENSMUSG00000031392 and 16179, IRAK1 and IDBG-632573 and ENSBTAG00000016085 and 533953

Gene info

• Identity
  HGNC:6112
• Gene
  IRAK1
• Long gene name
  interleukin 1 receptor associated kinase 1
• Synonyms
  • IRAK
  • pelle
• GenBank acession
  • L76191
• Locus
  Xq28
• Discovery year
  1998-06-22
• Entrez gene record
  3654
• Pubmed identfication
  • 9374458
  • 8599092
• VEGA ID
  OTTHUMG00000024228
• Locus Specific Databases
  • Global Variome shared LOVD

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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