HRG Antibody

• Catalog number
  R31633
• Price
  Please ask
• Size
  0.1mg

• Category
  Antibody
• Concentration
  0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  HRG
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, IHC-P
• Recommended dilutions
  Western blot: 0.5-1ug/ml,IHC (Paraffin): 0.5-1ug/ml
• Notes
  The stated application concentrations are suggested starting amounts. Titration of the HRG antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This HRG antibodyis to be used only for research purposes and not for diagnostics..
• Gene ID
  3273
• Purity
  Antigen affinity
• Description
  Histidine-rich glycoprotein is a protein that in humans is encoded by the HRG gene. It is mapped to 3q27.3. HRG contains two cystatin-like domains and is located in plasma and platelets. The protein can bind heme, dyes and divalent metal ions. It also can inhibit rosette formation and interacts with heparin, thrombospondin and plasminogen. Two of the proteins effects, the inhibition of fibrinolysis and the reduction of inhibition of coagulation, indicate a potential prothrombotic effect. Mutations in this gene lead to thrombophilia due to abnormal histidine-rich glycoprotein levels. HRG is thought to have multiple roles as a protein in the human blood, including roles in immunity, angiogenesis and coagulation.
• Immunogen
  Human partial recombinant protein (AA 19-200) was used as the immunogen for this HRG antibody.
• Storage
  After reconstitution, the HRG antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  HRG  
• Gene symbol
  HRG-AS1, HRG, NRG1
• Short name
  Anti-HRG
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibodies to HRG
• Alternative technique
  antibodies
• Alternative to gene target
  histidine-rich glycoprotein, HPRG and HRGP and THPH11, HRG and IDBG-69039 and ENSG00000113905 and 3273, metal ion binding, Extracellular, Hrg and IDBG-148872 and ENSMUSG00000022877 and 94175, HRG and IDBG-634671 and ENSBTAG00000001265 and 101909599,280820

Gene info

• Identity
  HGNC:55915
• Gene
  HRG-AS1
• Long gene name
  HRG and FETUB antisense RNA 1
• Locus
  3q27.3
• Discovery year
  2021-10-11
• Entrez gene record
  105374258
• Classification
  • Antisense RNAs

Gene info

• Identity
  HGNC:5181
• Gene
  HRG
• Long gene name
  histidine rich glycoprotein
• Synonyms gene name
  • histidine-rich glycoprotein
• Synonyms
  • HRGP
  • HPRG
• Synonyms name
  • histidine-proline rich glycoprotein
  • thrombophilia due to elevated HRG
• Locus
  3q27.3
• Discovery year
  1989-05-25
• Entrez gene record
  3273
• Pubmed identfication
  • 1678514
• RefSeq identity
  • NM_000412
• Classification
  • Cystatins, type 4
• VEGA ID
  OTTHUMG00000156578
• Locus Specific Databases
  • LRG_601

Gene info

• Identity
  HGNC:7997
• Gene
  NRG1
• Long gene name
  neuregulin 1
• Synonyms gene
  • HGL
  • NRG1-IT2
• Synonyms gene name
  • NRG1 intronic transcript 2 (non-protein coding)
• Synonyms
  • HRG
  • NDF
  • GGF
• GenBank acession
  • L12261
• Locus
  8p12
• Discovery year
  1999-03-19
• Entrez gene record
  3084
• Pubmed identfication
  • 1350381
  • 8095334
• Classification
  • I-set domain containing
  • Neuregulins
• VEGA ID
  OTTHUMG00000163918

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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