Hes1 Antibody
-
Catalog numberF52879-0.08ML
-
PricePlease ask
-
Size0.08 ml
-
-
CategoryAntibody
-
ConcentrationIn 1X PBS, pH 7.4, with 0.09% sodium azide
-
FormAntigen affinity purified
-
ConjugationUnconjugated
-
ClonePolyclonal antibody
-
Recognised antigenHes1
-
Host animalRabbit (Oryctolagus cuniculus)
-
ClonalityPolyclonal (rabbit origin)
-
Species reactivityMouse (Mus musculus) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
-
Tested applicationsWB, ELISA
-
Recommended dilutionsWestern blot: 1:1000
-
NotesTitration of the Hes1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
-
Intented useThis Hes1 antibodyis to be used only for research purposes and not for diagnostics..
-
UniprotP35428
-
PurityAntigen affinity
-
DescriptionTranscriptional repressor of genes that require a bHLH protein for their transcription. May act as a negative regulator of myogenesis by inhibiting the functions of MYOD1 and ASH1 (By similarity). Binds DNA on N-box motifs: 5'-CACNAG-3' with high affinity and on E-box motifs: 5'-CANNTG-3' with low affinity. May play a role in a functional FA core complex response to DNA cross- link damage, being required for the stability and nuclear localization of FA core complex proteins, as well as for FANCD2 monoubiquitination in response to DNA damage (By similarity).
-
ImmunogenThis mouse Hes1 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 102-137 amino acids from the Central region of mouse Hes1.
-
StorageAliquot the Hes1 antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
-
PropertiesIf you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
French translationanticorps
-
Gene target
-
Gene symbolHES1, GATD3
-
Short nameAnti-Hes1
-
TechniqueAntibody, antibodies against human proteins, antibodies for
-
IsotypeRabbit Ig
-
Alternative nameAntibodies to Hes1
-
Alternative techniqueantibodies
-
Alternative to gene targethairy and enhancer of split 1, (Drosophila), bHLHb39 and HES-1 and HHL and HRY, HES1 and IDBG-70185 and ENSG00000114315 and 3280, N-box binding, nuclei, Hes1 and IDBG-151888 and ENSMUSG00000022528 and 15205, HES1 and IDBG-634294 and ENSBTAG00000000569 and 539547
-
Gene info
-
Identity
-
Gene
-
Long gene namehes family bHLH transcription factor 1
-
Synonyms gene
-
Synonyms gene name
- hairy homolog (Drosophila)
- hairy and enhancer of split 1, (Drosophila)
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year1993-09-21
-
Entrez gene record
-
Pubmed identfication
-
Classification
- Basic helix-loop-helix proteins
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameglutamine amidotransferase class 1 domain containing 3
-
Synonyms gene
-
Synonyms gene name
- chromosome 21 open reading frame 33
- glutamine amidotransferase like class 1 domain containing 3A
- glutamine amidotransferase class 1 domain containing 3A
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year2000-05-23
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Glutamine amidotransferase class 1 domain containing
-
VEGA ID
MeSH Data
-
Name
-
ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
