GLUT1 Antibody / SLC2A1

• Catalog number
  R31941
• Price
  Please ask
• Size
  0.1mg

• Category
  Antibody
• Concentration
  0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  GLUT1 / SLC2A1
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens), Mouse (Mus musculus), Rat ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, IHC-P, IHC-F, ICC
• Recommended dilutions
  Western blot: 0.1-0.5ug/ml,Immunocytochemistry: 0.5-1ug/ml,IHC (Frozen): 0.5-1ug/ml,IHC (Paraffin): 0.5-1ug/ml
• Notes
  Optimal dilution of the SLC2A1 antibody should be determined by the researcher.
• Intented use
  This SLC2A1 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  P11166
• Purity
  Antigen affinity
• Description
  GLUT1, also known as SLC2A1, is a major glucose transporter in the mammalian blood-brain barrier whose gene is mapped to 1p35-p31.3 and contains 10 exons. It is present at high levels in primate erythrocytes and brain endothelial cells. Not only can transport dehydroascorbic acid (the oxidized form of vitamin C) into the brain, GLUT1 is also likely to contribute to HTLV-associated disorders through interacting with HTLV envelope glycoproteins. Functionally, GLUT1 deficiency causes a decrease in embryonic glucose uptake and apoptosis, which may be involved in diabetic embryopathy, by contrast, an increased expression of GLUT1 in some malignant tumors may suggest a role for glucose-derivative tracers to detect in vivo thyroid cancer metastases by positron-emission tomography scanning.
• Immunogen
  Amino acids 92-492 of human SLC2A1 were used as the immunogen for the SLC2A1 antibody.
• Storage
  After reconstitution, the SLC2A1 antibody may be kept for up to one month refrigerated at +4 degrees C.For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
• Localization
  Cytoplasmic, membrane
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  GLUT1   SLC2A1  
• Gene symbol
  SLC2A1, SLC2A1-DT
• Short name
  Anti-GLUT1 / SLC2A1
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibodies to GLUT1 / SLC2A1
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:11005
• Gene
  SLC2A1
• Long gene name
  solute carrier family 2 member 1
• Synonyms gene
  • GLUT1
  • GLUT
  • HTLVR
  • CSE
• Synonyms gene name
  • human T-cell leukemia virus (I and II) receptor
  • choreoathetosis/spasticity, episodic (paroxysmal choreoathetosis/spasticity)
  • solute carrier family 2 (facilitated glucose transporter), member 1
• Synonyms
  • DYT18
  • DYT9
• GenBank acession
  • K03195
• Locus
  1p34.2
• Discovery year
  1994-11-18
• Entrez gene record
  6513
• Pubmed identfication
  • 8839927
  • 14622599
  • 18451999
  • 21832227
• RefSeq identity
  • NM_006516
• Classification
  • Solute carriers
• VEGA ID
  OTTHUMG00000007657
• Locus Specific Databases
  • LRG_1132

Gene info

• Identity
  HGNC:44187
• Gene
  SLC2A1-DT
• Long gene name
  SLC2A1 divergent transcript
• Synonyms gene
  • SLC2A1-AS1
• Synonyms gene name
  • SLC2A1 antisense RNA 1 (non-protein coding)
  • SLC2A1 antisense RNA 1
• GenBank acession
  • AK056786
• Locus
  1p34.2
• Discovery year
  2012-06-30
• Entrez gene record
  440584
• RefSeq identity
  • NR_033967
• Classification
  • Divergent transcripts
• VEGA ID
  OTTHUMG00000007699

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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