FOXP2 Antibody

• Catalog number
  F49315-0.08ML
• Price
  Please ask
• Size
  0.08 ml

• Category
  Antibody
• Concentration
  In 1X PBS pH 7.4 with 0.09% sodium azide
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  FOXP2
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens), Mouse (Mus musculus) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, IF, ELISA
• Recommended dilutions
  Western blot: 1:1000,Immunofluorescence: 1:10-1:50
• Notes
  Titration of the FOXP2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This FOXP2 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  O15409
• Purity
  Antigen affinity
• Description
  FOXP2 is a member of the forkhead/winged-helix (FOX) family of transcription factors. It is expressed in fetal and adult brain as well as in several other organs such as the lung and gut. The protein product contains a FOX DNA-binding domain and a large polyglutamine tract and is an evolutionarily conserved transcription factor, which may bind directly to approximately 300 to 400 gene promoters in the human genome to regulate the expression of a variety of genes. This gene is required for proper development of speech and language regions of the brain during embryogenesis, and may be involved in a variety of biological pathways and cascades that may ultimately influence language development. Mutations in this gene cause speech-language disorder 1 (SPCH1), also known as autosomal dominant speech and language disorder with orofacial dyspraxia. Multiple alternative transcripts encoding different isoforms have been identified in this gene.
• Immunogen
  A portion of amino acids 657-684 from the human protein was used as the immunogen for this FOXP2 antibody.
• Storage
  Aliquot the FOXP2 antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  FOXP2  
• Gene symbol
  FOXP2
• Short name
  Anti-FOXP2
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit Ig
• Alternative name
  Antibodies to FOXP2
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:13875
• Gene
  FOXP2
• Long gene name
  forkhead box P2
• Synonyms gene
  • TNRC10
  • SPCH1
• Synonyms
  • CAGH44
• Synonyms name
  • trinucleotide repeat containing 10
  • forkhead/winged-helix transcription factor
  • speech and language disorder 1
  • CAG repeat protein 44
• GenBank acession
  • U80741
• Locus
  7q31.1
• Discovery year
  2000-11-20
• Entrez gene record
  93986
• Pubmed identfication
  • 11586359
  • 9225980
• RefSeq identity
  • NM_014491
• Classification
  • MicroRNA protein coding host genes
  • Forkhead boxes
• VEGA ID
  OTTHUMG00000023131

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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