FOXM1 Antibody

• Catalog number
  R31607
• Price
  Please ask
• Size
  0.1mg

• Category
  Antibody
• Concentration
  0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  FOXM1
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB
• Recommended dilutions
  Western blot: 0.5-1ug/ml
• Notes
  The stated application concentrations are suggested starting amounts. Titration of the FOXM1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This FOXM1 antibodyis to be used only for research purposes and not for diagnostics..
• Gene ID
  2305
• Purity
  Antigen affinity
• Description
  Forkhead box protein M1 is encoded by the FOXM1 gene. It is a member of the FOX family of transcription factors. FOXM1 is known to play a key role in cell cycle progression where endogenous FOXM1 expression peaks at S and G2/M phases and also in the control of cell proliferation. The gene is now known as a human proto-oncogene. Abnormal upregulation of the protein is involved in the oncogenesis of basal cell carcinoma, the most common human cancer worldwide. It is hypothesized that FOXM1 induces cancer initiation through stem/progenitor cell expansion. Additionally, FOXM1 has been shown to modulate the epigenome. It was found that overexpression of the protein brain washes normal cells to adopt cancer-like epigenome.
• Immunogen
  Human partial recombinant protein (AA 411-763) was used as the immunogen for this FOXM1 antibody.
• Storage
  After reconstitution, the FOXM1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  FOXM1  
• Gene symbol
  FOXM1
• Short name
  Anti-FOXM1
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibodies to FOXM1
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:3818
• Gene
  FOXM1
• Long gene name
  forkhead box M1
• Synonyms gene
  • FKHL16
• Synonyms
  • HFH-11
  • trident
  • HNF-3
  • INS-1
  • MPP2
  • MPHOSPH2
  • TGT3
• Synonyms name
  • M-phase phosphoprotein 2
• GenBank acession
  • Y12773
• Locus
  12p13.33
• Discovery year
  1997-07-25
• Entrez gene record
  2305
• Pubmed identfication
  • 9032290
  • 9441747
• RefSeq identity
  • NM_021953
• Classification
  • Forkhead boxes
• VEGA ID
  OTTHUMG00000168118

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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