ErbB2 Antibody

• Catalog number
  F50600-0.4ML
• Price
  Please ask
• Size
  0.4 ml

• Category
  Antibody
• Concentration
  In 1X PBS, pH 7.4, with 0.09% sodium azide
• Form
  Purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  ErbB2
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, FACS, IHC, ELISA
• Recommended dilutions
  Western blot: 1:1000,Flow Cytometry: 1:10-1:50,IHC (Paraffin): 1:50-1:100
• Notes
  Titration of the ErbB2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This ErbB2 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  P04626
• Purity
  Purified
• Description
  ErbB2, a member of the EGF receptor family, is an essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. This protein is not activated by EGF, TGF-alpha and amphiregulin. ErbB2 potentially forms a heterodimer with each of the other ERBB receptors. An Interaction with PRKCABP has been suggested. Ligand-binding to this Type I membrane protein may increase phosphorylation on tyrosine residues
• Immunogen
  A portion of amino acids 21-52 from the human protein was used as the immunogen for this ErbB2 antibody.
• Storage
  Aliquot the ErbB2 antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  ErbB2  
• Gene symbol
  ERBIN, TOB2P1, TOB1
• Short name
  Anti-ErbB2
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit Ig
• Alternative name
  Antibodies to ErbB2
• Alternative technique
  antibodies
• Alternative to gene target
  v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian), CD340 and HER-2 and HER-2/neu and HER2 and MLN 19 and NEU and NGL and TKR1, ERBB2 and IDBG-46068 and ENSG00000141736 and 2064, transferase activity, nuclei, Erbb2 and IDBG-210591 and ENSMUSG00000062312 and 13866, ERBB2 and IDBG-639410 and ENSBTAG00000021798 and 505709

Gene info

• Identity
  HGNC:15842
• Gene
  ERBIN
• Long gene name
  erbb2 interacting protein
• Synonyms gene
  • ERBB2IP
• Synonyms gene name
  • erbb2-interacting protein
• Synonyms
  • LAP2
• Synonyms name
  • densin-180-like protein
  • ERBB2-interacting protein
• Locus
  5q12.3
• Discovery year
  2001-06-18
• Entrez gene record
  55914
• Pubmed identfication
  • 10574462
  • 10878805
• RefSeq identity
  • NM_018695
• Classification
  • PDZ domain containing
• VEGA ID
  OTTHUMG00000097808

Gene info

• Identity
  HGNC:13986
• Gene
  TOB2P1
• Long gene name
  transducer of ERBB2, 2 pseudogene 1
• Synonyms gene
  • TOB2P
• Synonyms gene name
  • transducer of ERBB2, 2 pseudogene
• Synonyms
  • TOB4p
  • p373c6.3
• GenBank acession
  • BC050562
• Locus
  6p22.1
• Discovery year
  2003-11-27
• Entrez gene record
  222699
• Pubmed identfication
  • 12477932
• RefSeq identity
  • NR_002936
• VEGA ID
  OTTHUMG00000014512

Gene info

• Identity
  HGNC:11979
• Gene
  TOB1
• Long gene name
  transducer of ERBB2, 1
• Synonyms gene
  • TROB1
• Synonyms
  • TOB
  • TROB
  • APRO5
• GenBank acession
  • D38305
• Locus
  17q21.33
• Discovery year
  2000-06-01
• Entrez gene record
  10140
• Pubmed identfication
  • 8632892
  • 17785442
• Classification
  • BTG/Tob family
• VEGA ID
  OTTHUMG00000162277

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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