EDNRB Antibody

• Catalog number
  R32027
• Price
  Please ask
• Size
  0.1mg

• Category
  Antibody
• Concentration
  0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  EDNRB
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens), Mouse (Mus musculus), Rat ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, IHC-P
• Recommended dilutions
  Western blot: 0.1-0.5ug/ml,IHC (Paraffin): 0.5-1ug/ml
• Notes
  Optimal dilution of the EDNRB antibody should be determined by the researcher.
• Intented use
  This EDNRB antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  P24530
• Purity
  Antigen affinity
• Description
  Endothelin receptor type B, also known as ETB, is a protein that in humans is encoded by the EDNRB gene. The protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
• Immunogen
  Amino acids QSFEEKQSLEEKQSCLKFKANDHGYDNFRSSNKY of human EDNRB were used as the immunogen for the EDNRB antibody.
• Storage
  After reconstitution, the EDNRB antibody may be kept for up to one month refrigerated at +4 degrees C.For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
• Localization
  Cytoplasmic, membrane
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  EDNRB  
• Gene symbol
  EDNRB-AS1, EDNRB
• Short name
  Anti-EDNRB
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibodies to EDNRB
• Alternative technique
  antibodies
• Alternative to gene target
  endothelin receptor type B, ABCDS and ET-B and ET-BR and ETB and ETBR and ETRB and HSCR and HSCR2 and WS4A, EDNRB and IDBG-40388 and ENSG00000136160 and 1910, type 1 angiotensin receptor binding, nuclei, Ednrb and IDBG-185332 and ENSMUSG00000022122 and 13618, EDNRB and IDBG-631994 and ENSBTAG00000005299 and 281750

Gene info

• Identity
  HGNC:49045
• Gene
  EDNRB-AS1
• Long gene name
  EDNRB antisense RNA 1
• GenBank acession
  • BC031243
• Locus
  13q22.3
• Discovery year
  2013-08-15
• Entrez gene record
  100505518
• RefSeq identity
  • NR_103853
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000017113

Gene info

• Identity
  HGNC:3180
• Gene
  EDNRB
• Long gene name
  endothelin receptor type B
• Synonyms gene
  • HSCR2
  • HSCR
• Synonyms
  • ETB
• GenBank acession
  • L06623
• Locus
  13q22.3
• Discovery year
  1992-02-13
• Entrez gene record
  1910
• Pubmed identfication
  • 1659806
  • 9556633
• Classification
  • Endothelin receptors
• VEGA ID
  OTTHUMG00000017111
• Locus Specific Databases
  • Global Variome shared LOVD

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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