EDN3 Antibody

• Catalog number
  F40093-0.4ML
• Price
  Please ask
• Size
  0.4 ml

• Category
  Antibody
• Concentration
  In 1X PBS, pH 7.4, with 0.09% sodium azide
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  EDN3
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, ELISA
• Recommended dilutions
  Western blot: 1:1000
• Notes
  Titration of the EDN3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This EDN3 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  P14138
• Purity
  Antigen affinity
• Description
  The protein encoded by this gene is a member of the endothelin family. Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions. The active form of this protein is a 21 amino acid peptide processed from the precursor protein. The active peptide is a ligand for endothelin receptor type B (EDNRB). The interaction of this endothelin with EDNRB is essential for development of neural crest-derived cell lineages, such as melanocytes and enteric neurons. Mutations in this gene and EDNRB have been associated with Hirschsprung disease (HSCR) and Waardenburg syndrome (WS), which are congenital disorders involving neural crest-derived cells. Four alternatively spliced transcript variants encoding three distinct isoforms have been observed.
• Immunogen
  A portion of amino acids 168-197 from the human protein was used as the immunogen for this EDN3 antibody.
• Storage
  Aliquot the EDN3 antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  EDN3  
• Gene symbol
  EDN3
• Short name
  Anti-EDN3
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit Ig
• Alternative name
  Antibodies to EDN3
• Alternative technique
  antibodies
• Alternative to gene target
  endothelin 3, ET-3 and ET3 and HSCR4 and PPET3 and WS4B, EDN3 and IDBG-83422 and ENSG00000124205 and 1908, hormone activity, Extracellular, Edn3 and IDBG-213499 and ENSMUSG00000027524 and 13616, EDN3 and IDBG-641126 and ENSBTAG00000012109 and

Gene info

• Identity
  HGNC:3178
• Gene
  EDN3
• Long gene name
  endothelin 3
• Synonyms
  • ET3
• GenBank acession
  • X52001
• Locus
  20q13.32
• Discovery year
  1989-09-06
• Entrez gene record
  1908
• RefSeq identity
  • NM_000114
• Classification
  • Endothelins
• VEGA ID
  OTTHUMG00000032867
• Locus Specific Databases
  • Global Variome shared LOVD
  • LRG_1381

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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