EDA Antibody

• Catalog number
  R31604
• Price
  Please ask
• Size
  0.1mg

• Category
  Antibody
• Concentration
  0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  EDA
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB
• Recommended dilutions
  Western blot: 0.5-1ug/ml
• Notes
  The stated application concentrations are suggested starting amounts. Titration of the EDA antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This EDA antibodyis to be used only for research purposes and not for diagnostics..
• Gene ID
  1896
• Purity
  Antigen affinity
• Description
  Ectodysplasin-A is a protein that in humans is encoded by the EDA gene. It is mapped to Xq13.1. The protein encoded by this gene is a type II membrane protein that can be cleaved by furin to produce a secreted form. The encoded protein, which belongs to the tumor necrosis factor family, acts as a homotrimer and may be involved in cell-cell signaling during the development of ectodermal organs. Defects in this gene are a cause of ectodermal dysplasia, anhidrotic, which is also known as X-linked hypohidrotic ectodermal dysplasia.
• Immunogen
  Human partial recombinant protein (AA 30-391) was used as the immunogen for this EDA antibody.
• Storage
  After reconstitution, the EDA antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  EDA  
• Gene symbol
  EDA, EDA2R
• Short name
  Anti-EDA
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibodies to EDA
• Alternative technique
  antibodies
• Alternative to gene target
  ectodysplasin A, ECTD1 and ED1 and ED1-A1 and ED1-A2 and EDA-A1 and EDA-A2 and EDA1 and EDA2 and HED and HED1 and ODT1 and STHAGX1 and XHED and XLHED, EDA and IDBG-74170 and ENSG00000158813 and 1896, protein binding, Extracellular, Eda and IDBG-161929 and ENSMUSG00000059327 and 13607, EDA and IDBG-636361 and ENSBTAG00000012543 and 616179

Gene info

• Identity
  HGNC:3157
• Gene
  EDA
• Long gene name
  ectodysplasin A
• Synonyms gene
  • ED1
  • EDA2
  • ODT1
• Synonyms gene name
  • ectodermal dysplasia 1, anhidrotic
  • oligodontia 1
• Synonyms
  • EDA1
  • XLHED
  • HED
  • XHED
  • ED1-A1
  • ED1-A2
  • EDA-A1
  • EDA-A2
• GenBank acession
  • U59227
• Locus
  Xq13.1
• Discovery year
  2001-06-22
• Entrez gene record
  1896
• Pubmed identfication
  • 8696334
  • 18657636
  • 16583127
• RefSeq identity
  • NM_001399
• Classification
  • MicroRNA protein coding host genes
  • Tumor necrosis factor superfamily
• VEGA ID
  OTTHUMG00000021764
• Locus Specific Databases
  • Global Variome shared LOVD

Gene info

• Identity
  HGNC:17756
• Gene
  EDA2R
• Long gene name
  ectodysplasin A2 receptor
• Synonyms
  • XEDAR
  • EDA-A2R
  • EDAA2R
  • TNFRSF27
• GenBank acession
  • AF298812
• Locus
  Xq12
• Discovery year
  2004-08-17
• Entrez gene record
  60401
• Pubmed identfication
  • 11039935
• RefSeq identity
  • NM_021783
• Classification
  • Tumor necrosis factor receptor superfamily
• VEGA ID
  OTTHUMG00000021736
• Locus Specific Databases
  • Global Variome shared LOVD

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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