EBP1 Antibody / ErbB3-binding protein 1

• Catalog number
  R32616
• Price
  Please ask
• Size
  0.1mg

• Category
  Antibody
• Concentration
  0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  EBP1 / ErbB3-binding protein 1
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens), Mouse (Mus musculus), Rat ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, IHC-P
• Recommended dilutions
  Western blot: 0.5-1ug/ml,Immunohistochemistry (FFPE): 1-2ug/ml
• Notes
  Optimal dilution of the EBP1 antibody should be determined by the researcher.
• Added buffer
  Lyophilized from 1X Phosphate Buffered Saline (PBS) with 2.5% BSA and 0.025% sodium azide
• Intented use
  This antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  Q9UQ80
• Purity
  Antigen affinity
• Description
  Proliferation-associated protein 2G4 (PA2G4), also known as ErbB3-binding protein 1 (EBP1), is a protein that in humans is encoded by the PA2G4 gene. This gene encodes an RNA-binding protein that is involved in growth regulation. This protein is present in pre-ribosomal ribonucleoprotein complexes and may be involved in ribosome assembly and the regulation of intermediate and late steps of rRNA processing. This protein can interact with the cytoplasmic domain of the ErbB3 receptor and may contribute to transducing growth regulatory signals. This protein is also a transcriptional corepressor of androgen receptor-regulated genes and other cell cycle regulatory genes through its interactions with histone deacetylases.
• Immunogen
  Amino acids 138-178 (RKADVIKAAHLCAEAALRLVKPGNQNTQVTEAWNKVAHSFN-human) were used as the immunogen for the EBP1 antibody.
• Storage
  After reconstitution, the EBP1 antibody may be kept for up to one month refrigerated at +4 degrees C.For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  EBP1   ErbB3-binding   protein  
• Gene symbol
  PA2G4
• Short name
  Anti- EBP1 / ErbB3-binding protein 1
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibodies to EBP1 / ErbB3-binding protein 1
• Alternative technique
  antibodies
• Alternative to gene target
  v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian), c-erbB-3 and c-erbB3 and ErbB-3 and erbB3-S and HER3 and LCCS2 and MDA-BF-1 and p180-ErbB3 and p45-sErbB3 and p85-sErbB3, ERBB3 and IDBG-39824 and ENSG00000065361 and 2065, transferase activity, Extracellular, Erbb3 and IDBG-197943 and ENSMUSG00000018166 and 13867, ERBB3 and IDBG-636302 and ENSBTAG00000010444 and 785655

Gene info

• Identity
  HGNC:8550
• Gene
  PA2G4
• Long gene name
  proliferation-associated 2G4
• Synonyms gene name
  • proliferation-associated 2G4, 38kD
  • proliferation-associated 2G4, 38kDa
• Synonyms
  • EBP1
• Synonyms name
  • ErbB-3 receptor binding protein
• GenBank acession
  • U59435
  • BC007561
• Locus
  12q13.2
• Discovery year
  1996-10-26
• Entrez gene record
  5036
• Pubmed identfication
  • 9345902
  • 17765895
  • 32952126
• RefSeq identity
  • NM_006191
• Classification
  • M24 metallopeptidase family
• VEGA ID
  OTTHUMG00000170173

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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