CYP1A1 Antibody

• Catalog number
  F50940-0.4ML
• Price
  Please ask
• Size
  0.4 ml

• Category
  Antibody
• Concentration
  In 1X PBS, pH 7.4, with 0.09% sodium azide
• Form
  Purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  CYP1A1
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens), Mouse (Mus musculus) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, IF, IHC, ELISA
• Recommended dilutions
  Western blot: 1:1000,Immunofluorescence: 1:10-1:50,IHC (Paraffin): 1:10-1:50
• Notes
  Titration of the CYP1A1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This CYP1A1 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  P04798
• Purity
  Purified
• Description
  CYP1A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. CYP1A1 gene has been associated with lung cancer risk.
• Immunogen
  A portion of amino acids 252-280 from the human protein was used as the immunogen for this CYP1A1 antibody.
• Storage
  Aliquot the CYP1A1 antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  CYP1A1  
• Gene symbol
  CYP1A1
• Short name
  Anti-CYP1A1
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit Ig
• Alternative name
  Antibodies to CYP1A1
• Alternative technique
  antibodies
• Alternative to gene target
  cytochrome P450, family 1, subfamily A, polypeptide 1, AHH and AHRR and CP11 and CYP1 and P1-450 and P450-C and P450DX, CYP1A1 and IDBG-22475 and ENSG00000140465 and 1543, oxidoreductase activity, Cytoplasm, Cyp1a1 and IDBG-170677 and ENSMUSG00000032315 and 13076, CYP1A1 and IDBG-631735 and ENSBTAG00000001021 and 282870

Gene info

• Identity
  HGNC:2595
• Gene
  CYP1A1
• Long gene name
  cytochrome P450 family 1 subfamily A member 1
• Synonyms gene
  • CYP1
• Synonyms gene name
  • cytochrome P450, subfamily I (aromatic compound-inducible), polypeptide 1
  • cytochrome P450, family 1, subfamily A, polypeptide 1
• Synonyms
  • P450DX
  • P1-450
  • P450-C
  • CP11
• GenBank acession
  • BC023019
• Locus
  15q24.1
• Discovery year
  1986-01-01
• Entrez gene record
  1543
• Pubmed identfication
  • 15128046
• RefSeq identity
  • NM_000499
• Classification
  • Cytochrome P450 family 1
• VEGA ID
  OTTHUMG00000142812
• Locus Specific Databases
  • PharmVar Human Cytochrome P450 (CYP) Allele Nomenclature
  • LRG_1262

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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