Clusterin Antibody
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Catalog numberR31938
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PricePlease ask
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Size0.1mg
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CategoryAntibody
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Concentration0.5mg/ml if reconstituted with 0.2ml sterile DI water
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FormAntigen affinity purified
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ConjugationUnconjugated
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ClonePolyclonal antibody
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Recognised antigenClusterin
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Host animalRabbit (Oryctolagus cuniculus)
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ClonalityPolyclonal (rabbit origin)
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Species reactivityHuman (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
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Tested applicationsWB, IHC-P, ELISA
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Recommended dilutionsWestern blot: 0.1-0.5ug/ml,IHC (Paraffin): 0.5-1ug/ml
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NotesOptimal dilution of the CLU antibody should be determined by the researcher.
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Intented useThis CLU antibodyis to be used only for research purposes and not for diagnostics..
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UniprotP10909
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PurityAntigen affinity
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DescriptionClusterin (apolipoprotein J) is a 75 - 80 kDa disulfide-linked heterodimeric protein associated with the clearance of cellular debris and apoptosis. In humans, clusterin is encoded by the CLU gene. This protein has several synonyms: dimeric acidic glycoprotein (DAG protein), testosterone repressed prostate message-2 (TRPM-2), sulfated glycoprotein-2 (SGP-2) and complement lysis inhibitor (CLI). Clusterin was mapped to mouse chromosome 14. Clusterin is a ubiquitously expressed molecule thought to influence a variety of processes including cell death. In the brain, it accumulates in dying neurons following seizures and hypoxic-ischemic (H-I) injury. clusterin may be a new therapeutic target to modulate non-caspase-dependent neuronal death following acute brain injury.
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ImmunogenAmino acids 228-449 of human Clusterin/Apolipoprotein J were used as the immunogen for the CLU antibody.
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StorageAfter reconstitution, the CLU antibody may be kept for up to one month refrigerated at +4 degrees C.For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
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LocalizationCytoplasmic
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PropertiesIf you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolCLUL1, CLU, CLUAP1
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Short nameAnti-Clusterin
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TechniqueAntibody, antibodies against human proteins, antibodies for
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IsotypeRabbit IgG
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Alternative nameAntibodies to Clusterin
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameclusterin like 1
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Synonyms gene name
- clusterin-like 1 (retinal)
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Synonyms name
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GenBank acession
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Locus
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Discovery year2000-05-30
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Entrez gene record
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Pubmed identfication
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameclusterin
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Synonyms gene
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Synonyms gene name
- clusterin (complement lysis inhibitor, SP-40,40, sulfated glycoprotein 2, testosterone-repressed prostate message 2, apolipoprotein J)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1990-07-26
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Complement system regulators and receptors
- MicroRNA protein coding host genes
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameclusterin associated protein 1
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2004-09-16
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- IFT-B2 complex
- Cilia and flagella associated
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data