Chromogranin A Antibody

• Catalog number
  V3273SAF-100UG
• Price
  Please ask
• Size
  0.1mg

• Category
  Antibody
• Concentration
  1 mg/ml in 1X PBS; BSA free, sodium azide free
• Form
  Purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  Chromogranin A
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens). Does not react with rat. Other species not tested. ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  FACS, IF, IHC-P
• Recommended dilutions
  Flow Cytometry: 0.5-1ug/million cells in 0.1ml,Immunofluorescence: 1-2ug/ml,Immunohistochemistry (FFPE): 0.25-0.5ug/ml for 30 min at RT
• Notes
  Optimal dilution of the Chromogranin A antibody should be determined by the researcher.
• Intented use
  This Chromogranin A antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  P10645
• Purity
  Purified by protein A Affinity Chromatography
• Description
  Chromogranin A is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, pheochromocytomas, paragangliomas, and other neuroendocrine tumors. Co-expression of Chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms. Reportedly, co-expression of certain keratins and chromogranin indicates neuroendocrine lineage. The presence of strong anti-chromogranin staining and absence of anti-keratin staining should raise the possibility of paraganglioma. The co-expression of chromogranin and NSE is typical of neuroendocrine neoplasms. Most pituitary adenomas and prolactinomas readily express chromogranin.
• Immunogen
  Recombinant human protein was used as the immunogen for the Chromogranin A antibody.
• Storage
  Store the Chromogranin A antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
• Localization
  Cytoplasmic
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Chromogranin  
• Gene symbol
  CHGA
• Short name
  Anti-Chromogranin A
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibodies to Chromogranin A
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:1929
• Gene
  CHGA
• Long gene name
  chromogranin A
• Synonyms name
  • vasostatin
  • pancreastatin
  • parastatin
  • parathyroid secretory protein 1
• Locus
  14q32.12
• Discovery year
  2001-06-22
• Entrez gene record
  1113
• Pubmed identfication
  • 3403545
• RefSeq identity
  • NM_001275
• Classification
  • Neuropeptides
  • Granins
• VEGA ID
  OTTHUMG00000171225

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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