CFD Antibody / Complement Factor D

• Catalog number
  R31875
• Price
  Please ask
• Size
  0.1mg

• Category
  Antibody
• Concentration
  0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  CFD / Complement Factor D
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Mouse (Mus musculus) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB
• Recommended dilutions
  Western blot: 0.1-0.5ug/ml
• Notes
  Optimal dilution of the Factor D antibody should be determined by the researcher.
• Intented use
  This Factor D antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  P03953
• Purity
  Antigen affinity
• Description
  Complement Factor D is a protein which in humans is encoded by the CFD gene. The protein encoded by this gene is a member of the trypsin family of peptidases. The encoded protein is a component of the alternative complement pathway best known for its role in humoral suppression of infectious agents. It is also a serine protease that is secreted by adipocytes into the bloodstream. And it stimulates glucose transport for triglyceride accumulation in fats cells and inhibits lipolysis. Finally, the encoded protein has a high level of expression in fat, suggesting a role for adipose tissue in immune system biology.
• Immunogen
  Amino acids 30-235 of mouse Factor D were used as the immunogen for the Factor D antibody.
• Storage
  After reconstitution, the Factor D antibody may be kept for up to one month refrigerated at +4 degrees C.For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Additional description
  Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells.
• French translation
  anticorps

• Gene target
  CFD   Complement   Factor  
• Gene symbol
  CFD
• Short name
  Anti-CFD / Complement Factor D
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibodies to CFD / Complement Factor D
• Alternative technique
  antibodies
• Alternative to gene target
  complement factor D (adipsin), ADIPSIN and ADN and DF and PFD, CFD and IDBG-13129 and ENSG00000197766 and 1675, serine-type peptidase activity, Extracellular, Cfd and IDBG-171424 and ENSMUSG00000061780 and 11537

Gene info

• Identity
  HGNC:2771
• Gene
  CFD
• Long gene name
  complement factor D
• Synonyms gene
  • DF
  • PFD
• Synonyms gene name
  • D component of complement (adipsin)
  • properdin factor D
  • complement factor D (adipsin)
• Synonyms
  • ADN
• Synonyms name
  • adipsin
• GenBank acession
  • M84526
• Locus
  19p13.3
• Discovery year
  1992-10-21
• Entrez gene record
  1675
• Pubmed identfication
  • 1374388
• RefSeq identity
  • NM_001928
• Classification
  • Granule associated serine proteases of immune defence
  • Complement system activation components
• VEGA ID
  OTTHUMG00000181840
• Locus Specific Databases
  • CFDbase: Mutation registry for Factor D deficiency (previously known as DFbase)
  • LRG_46

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Similar products