Cdc37 Antibody

#

• Catalog number
  R31256
• Price:

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• Size
  0.1mg

# #

• Category
  Antibody
• Concentration
  0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  Cdc37
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB
• Recommended dilutions
  Western blot: 0.5-1ug/ml
• Notes
  The stated application concentrations are suggested starting amounts. Titration of the Cdc37 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This Cdc37 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  Q16543
• Purity
  Antigen affinity
• Description
  Hsp90 co-chaperone Cdc37 is a protein that in humans is encoded by the CDC37 gene. The protein encoded by this gene is highly similar to Cdc 37, a cell division cycle control protein of Sacchromyces cerevisiae. This gene is mapped to 19p13.2. This protein is a molecular chaperone with specific function in cell signal transduction. It has been shown to form complex with Hsp90 and a variety of protein kinases including CDK4, CDK6, SRC, RAF-1, MOK, as well as eIF2 alpha kinases. It is though to play a critical role in directing Hsp90 to its target kinases.
• Immunogen
  An amino acid sequence from the C-terminus of human Cdc37 (DPLLEAVPKTGDEKDV) was used as the immunogen for this Cdc37 antibody.
• Storage
  After reconstitution, the Cdc37 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

#

• Gene target
  Cdc37  
• Gene symbol
  CDC37, CDC37L1
• Short name
  Anti-Cdc37
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibodies to Cdc37
• Alternative technique
  antibodies
• Alternative to gene target
  cell division cycle 37 homolog (S. cerevisiae), P50CDC37, CDC37 and IDBG-27267 and ENSG00000105401 and 11140, Hsp90 protein binding, Cytoplasm, Cdc37 and IDBG-139272 and ENSMUSG00000019471 and 12539, CDC37 and IDBG-643270 and ENSBTAG00000011699 and

Gene info

• Identity
  HGNC:1735
• Gene
  CDC37
• Long gene name
  cell division cycle 37, HSP90 cochaperone
• Synonyms gene name
  • CDC37 (cell division cycle 37, S. cerevisiae, homolog)
  • CDC37 cell division cycle 37 homolog (S. cerevisiae)
  • cell division cycle 37 homolog (S. cerevisiae)
• Synonyms
  • P50CDC37
• Synonyms name
  • CDC37 cell division cycle 37 homolog
  • Hsp90 co-chaperone Cdc37
  • CDC37 (cell division cycle 37, S. cerevisiae, homolog)
• GenBank acession
  • U63131
• Locus
  19p13.2
• Discovery year
  1999-09-07
• Entrez gene record
  11140
• Pubmed identfication
  • 8703009
  • 8666233
• RefSeq identity
  • NM_007065
• Classification
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000180578

Gene info

• Identity
  HGNC:17179
• Gene
  CDC37L1
• Long gene name
  cell division cycle 37 like 1
• Synonyms gene name
  • CDC37 cell division cycle 37 homolog (S. cerevisiae)-like 1
  • cell division cycle 37 homolog (S. cerevisiae)-like 1
  • cell division cycle 37-like 1
• Synonyms
  • HARC
  • FLJ20639
  • CDC37B
• GenBank acession
  • AK000497
• Locus
  9p24.1
• Discovery year
  2004-05-27
• Entrez gene record
  55664
• RefSeq identity
  • NM_017913
• VEGA ID
  OTTHUMG00000019465

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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