CD70 Antibody

• Catalog number
  F44122-0.4ML
• Price
  Please ask
• Size
  0.4 ml

• Category
  Antibody
• Concentration
  In 1X PBS, pH 7.4, with 0.09% sodium azide
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  CD70
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, IHC, ELISA
• Recommended dilutions
  Western blot: 1:1000,IHC (Paraffin): 1:10-1:50
• Notes
  Titration of the CD70 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This CD70 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  P32970
• Purity
  Antigen affinity
• Description
  The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis.
• Immunogen
  A portion of amino acids 72-101 from the human protein was used as the immunogen for this CD70 antibody.
• Storage
  Aliquot the CD70 antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  CD70  
• Gene symbol
  CD70
• Short name
  Anti-CD70
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit Ig
• Alternative name
  Antibodies to CD70
• Alternative technique
  antibodies
• Alternative to gene target
  CD70 molecule, CD27L and CD27LG and TNFSF7, CD70 and IDBG-21699 and ENSG00000125726 and 970, protein binding, Extracellular, Cd70 and IDBG-193725 and ENSMUSG00000019489 and 21948, CD70 and IDBG-643945 and ENSBTAG00000009752 and 522074

Gene info

• Identity
  HGNC:11937
• Gene
  CD70
• Long gene name
  CD70 molecule
• Synonyms gene
  • CD27LG
  • TNFSF7
• Synonyms gene name
  • tumor necrosis factor (ligand) superfamily, member 7
• Synonyms
  • CD27L
• GenBank acession
  • L08096
• Locus
  19p13.3
• Discovery year
  1993-11-08
• Entrez gene record
  970
• Pubmed identfication
  • 8387892
  • 8120384
• Classification
  • CD molecules
  • Tumor necrosis factor superfamily
• VEGA ID
  OTTHUMG00000181834

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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