Cd2 Antibody

• Catalog number
  R32420
• Price
  Please ask
• Size
  0.1mg

• Category
  Antibody
• Concentration
  0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  Cd2
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Mouse (Mus musculus) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, IHC-P
• Recommended dilutions
  Western blot: 0.1-0.5ug/ml,IHC (FFPE): 0.5-1ug/ml
• Notes
  Optimal dilution of the anti-Cd2 antibody should be determined by the researcher.
• Intented use
  This anti-Cd2 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  P08920
• Purity
  Antigen affinity
• Description
  CD2 (cluster of differentiation 2) is a cell adhesion molecule found on the surface of T cells and natural killer (NK) cells. It has also been called T-cell surface antigen T11/Leu-5, LFA-2, LFA-3 receptor, erythrocyte receptor and rosette receptor. Monoclonal antibodies directed against CD2 inhibit the formation of rosettes with sheep erythrocytes, indicating that CD2 is the erythrocyte receptor or is closely associated with it. CD2 is one of the earliest T-cell markers, being present on more than 95% of thymocytes. Due to its structural characteristics, CD2 is a member of the immunoglobulin superfamily; it possesses two immunoglobulin-like domains in its extracellular portion. The localization of CD2 to 1p13 is established by in situ hybridization. CD2 interacts with other adhesion molecules, such as lymphocyte function-associated antigen-3 (LFA-3/CD58) in humans, or CD48 in rodents, which are expressed on the surfaces of other cells. With the use of transgenic mice, such an LCR is identified within the 3-prime flanking region of the human CD2 gene.
• Immunogen
  Amino acids R23-S203 of the mouse protein were used as the immunogen for the anti-Cd2 antibody.
• Storage
  After reconstitution, the anti-Cd2 antibody may be kept for up to one month refrigerated at +4 degrees C.For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
• Localization
  Cytoplasmic, membranous
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Cd2  
• Gene symbol
  CD2, CD2AP, CD2BP2
• Short name
  Anti-Cd2
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibodies to Cd2
• Alternative technique
  antibodies
• Alternative to gene target
  CD2 molecule, LFA-2 and SRBC and T11, CD2 and IDBG-101417 and ENSG00000116824 and 914, protein homodimerization activity, Extracellular, Cd2 and IDBG-179684 and ENSMUSG00000027863 and 12481, CD2 and IDBG-634458 and ENSBTAG00000017256 and 497022

Gene info

• Identity
  HGNC:1639
• Gene
  CD2
• Long gene name
  CD2 molecule
• Synonyms gene
  • SRBC
• Synonyms gene name
  • CD2 antigen (p50), sheep red blood cell receptor
• GenBank acession
  • BC033583
• Locus
  1p13.1
• Discovery year
  1986-01-01
• Entrez gene record
  914
• Pubmed identfication
  • 2437578
• RefSeq identity
  • NM_001767
• Classification
  • CD molecules
  • Ig-like cell adhesion molecule family
  • C2-set domain containing
  • V-set domain containing
• VEGA ID
  OTTHUMG00000022750

Gene info

• Identity
  HGNC:14258
• Gene
  CD2AP
• Long gene name
  CD2 associated protein
• Synonyms
  • CMS
• GenBank acession
  • AF146277
• Locus
  6p12.3
• Discovery year
  2000-12-14
• Entrez gene record
  23607
• Pubmed identfication
  • 10339567
• VEGA ID
  OTTHUMG00000014799

Gene info

• Identity
  HGNC:1656
• Gene
  CD2BP2
• Long gene name
  CD2 cytoplasmic tail binding protein 2
• Synonyms gene name
  • CD2 antigen (cytoplasmic tail)-binding protein 2
  • CD2 (cytoplasmic tail) binding protein 2
• Synonyms
  • LIN1
  • Snu40
  • PPP1R59
  • U5-52K
• Synonyms name
  • protein phosphatase 1, regulatory subunit 59
• GenBank acession
  • AF104222
• Locus
  16p11.2
• Discovery year
  1999-06-18
• Entrez gene record
  10421
• Pubmed identfication
  • 9843987
• RefSeq identity
  • NM_006110
• Classification
  • Protein phosphatase 1 regulatory subunits
  • U5 small nuclear ribonucleoprotein
• VEGA ID
  OTTHUMG00000132397

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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