CD1e Antibody

• Catalog number
  F52013-0.4ML
• Price
  Please ask
• Size
  0.4 ml

• Category
  Antibody
• Concentration
  In 1X PBS, pH 7.4, with 0.09% sodium azide
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  CD1e
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, IHC, FACS, IF, ELISA
• Recommended dilutions
  Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50,Immunofluorescence: 1:10-1:50
• Notes
  Titration of the CD1e antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This CD1e antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  P15812
• Purity
  Antigen affinity
• Description
  CD1E encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes within Golgi compartments, endosomes, and lysosomes, and is cleaved into a stable soluble form. The soluble form is required for the intracellular processing of some glycolipids into a form that can be presented by other CD1 family members.
• Immunogen
  A portion of amino acids 184-212 from the human protein was used as the immunogen for this CD1e antibody.
• Storage
  Aliquot the CD1e antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  CD1e  
• Gene symbol
  CD1E
• Short name
  Anti-CD1e
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit Ig
• Alternative name
  Antibodies to CD1e
• Alternative technique
  antibodies
• Alternative to gene target
  CD1e molecule, CD1A and R2, CD1E and IDBG-103747 and ENSG00000158488 and 913, lipid binding, Plasma membranes, BT.49600 and IDBG-630922 and ENSBTAG00000009421 and 510832

Gene info

• Identity
  HGNC:1638
• Gene
  CD1E
• Long gene name
  CD1e molecule
• Synonyms gene name
  • CD1E antigen, e polypeptide
  • CD1e antigen
• GenBank acession
  • AJ289111
• Locus
  1q23.1
• Discovery year
  1990-06-11
• Entrez gene record
  913
• Pubmed identfication
  • 10948205
• RefSeq identity
  • NM_030893
• Classification
  • C1-set domain containing
  • CD molecules
• VEGA ID
  OTTHUMG00000017515

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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