CCR10 Antibody

• Catalog number
  F43216-0.08ML
• Price
  Please ask
• Size
  0.08 ml

• Category
  Antibody
• Concentration
  In 1X PBS, pH 7.4, with 0.09% sodium azide
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  CCR10
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, ELISA
• Recommended dilutions
  Western blot: 1:1000
• Notes
  Titration of the CCR10 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This CCR10 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  P46092
• Purity
  Antigen affinity
• Description
  Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC, based on the arrangement of the first 2 of the 4 conserved cysteine residues; the 2 cysteines are separated by a single amino acid in CXC chemokines and are adjacent in CC chemokines. CCR10 is the receptor for CCL27 (SCYA27; MIM 604833); CCR10-CCL27 interactions are involved in T cell-mediated skin inflammation (Homey et al., 2002 [PubMed 11821900]).
• Immunogen
  A portion of amino acids 1-30 from the human protein was used as the immunogen for this CCR10 antibody.
• Storage
  Aliquot the CCR10 antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  CCR10  
• Gene symbol
  CCR10, ACKR2
• Short name
  Anti-CCR10
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit Ig
• Alternative name
  Antibodies to CCR10
• Alternative technique
  antibodies
• Alternative to gene target
  chemokine (C-C motif) receptor 10, GPR2, CCR10 and IDBG-51414 and ENSG00000184451 and 2826, C-C chemokine receptor activity, Plasma membranes, Ccr10 and IDBG-211910 and ENSMUSG00000044052 and 12777, CCR10 and IDBG-640334 and ENSBTAG00000019095 and 539108

Gene info

• Identity
  HGNC:4474
• Gene
  CCR10
• Long gene name
  C-C motif chemokine receptor 10
• Synonyms gene
  • GPR2
• Synonyms gene name
  • G protein-coupled receptor 2
  • chemokine (C-C motif) receptor 10
• GenBank acession
  • AF215981
• Locus
  17q21.2
• Discovery year
  1994-07-25
• Entrez gene record
  2826
• Pubmed identfication
  • 7851889
• RefSeq identity
  • NM_016602
• Classification
  • C-C motif chemokine receptors
• VEGA ID
  OTTHUMG00000132301

Gene info

• Identity
  HGNC:1565
• Gene
  ACKR2
• Long gene name
  atypical chemokine receptor 2
• Synonyms gene
  • CMKBR9
  • CCBP2
• Synonyms gene name
  • chemokine binding protein 2
• Synonyms
  • CCR10
  • D6
  • CCR9
• GenBank acession
  • U94888
• Locus
  3p22.1
• Discovery year
  1998-04-28
• Entrez gene record
  1238
• Pubmed identfication
  • 9364936
  • 9405404
  • 16148
• RefSeq identity
  • NM_001296
• Classification
  • Atypical chemokine receptors
• VEGA ID
  OTTHUMG00000186377

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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