CCL2 Antibody

• Catalog number
  F49800-0.4ML
• Price
  Please ask
• Size
  0.4 ml

• Category
  Antibody
• Concentration
  In 1X PBS, pH 7.4, with 0.09% sodium azide
• Form
  Purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  CCL2
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, IHC, IF, FACS, ELISA
• Recommended dilutions
  Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Immunofluorescence: 1:10-1:50,Flow Cytometry: 1:10-1:50
• Notes
  Titration of the CCL2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This CCL2 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  P13500
• Purity
  Purified
• Description
  Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. CCL2 is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4.
• Immunogen
  A portion of amino acids 62-89 from the human protein was used as the immunogen for this CCL2 antibody.
• Storage
  Aliquot the CCL2 antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  CCL2  
• Gene symbol
  CCL2
• Short name
  Anti-CCL2
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit Ig
• Alternative name
  Antibodies to CCL2
• Alternative technique
  antibodies
• Alternative to gene target
  chemokine (C-C motif) ligand 2, GDCF-2 and HC11 and HSMCR30 and MCAF and MCP-1 and MCP1 and SCYA2 and SMC-CF, CCL2 and IDBG-40504 and ENSG00000108691 and 6347, CCR2 chemokine receptor binding, Extracellular, Ccl2 and IDBG-204473 and ENSMUSG00000035385 and 20296, CCL2 and IDBG-630954 and ENSBTAG00000037811 and 281043

Gene info

• Identity
  HGNC:10618
• Gene
  CCL2
• Long gene name
  C-C motif chemokine ligand 2
• Synonyms gene
  • SCYA2
• Synonyms gene name
  • small inducible cytokine A2 (monocyte chemotactic protein 1, homologous to mouse Sig-je)
  • chemokine (C-C motif) ligand 2
• Synonyms
  • MCP1
  • MCP-1
  • MCAF
  • SMC-CF
  • GDCF-2
  • HC11
  • MGC9434
• Synonyms name
  • monocyte chemotactic protein 1, homologous to mouse Sig-je
  • monocyte chemoattractant protein-1
  • monocyte chemotactic and activating factor
  • monocyte secretory protein JE
  • small inducible cytokine subfamily A (Cys-Cys), member 2
• GenBank acession
  • BC009716
• Locus
  17q12
• Discovery year
  1990-07-05
• Entrez gene record
  6347
• Pubmed identfication
  • 2004761
• RefSeq identity
  • NM_002982
• Classification
  • Chemokine ligands
• VEGA ID
  OTTHUMG00000132887

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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