CA2 Antibody / Carbonic Anhydrase II

• Catalog number
  R32474
• Price
  Please ask
• Size
  0.1mg

• Category
  Antibody
• Concentration
  0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  CA2 / Carbonic Anhydrase II
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens), Mouse (Mus musculus), Rat ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, IHC-P
• Recommended dilutions
  Western blot: 0.5-1ug/ml,IHC (FFPE): 1-2ug/ml
• Added buffer
  Lyophilized from 1X Phosphate Buffered Saline (PBS) with 2.5% BSA and 0.025% sodium azide
• Intented use
  This CA2 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  P00918
• Purity
  Antigen affinity
• Description
  CA2 is a cytosolic enzyme with the highest activity among all known CAs. The carbonic anhydrases (ACs) form a family of enzymes that catalyze the rapid interconversion of carbon dioxide and water to bicarbonate and protons (or vice versa), a reversible reaction that occurs relatively slowly in the absence of a catalyst. Mutations in the CA2 gene result in the CA II deficiency syndrome, an autosomal recessive disorder that produces osteopetrosis, renal tubular acidosis and cerebral calcification. This gene is mapped to 8q22.
• Immunogen
  Amino acids S2-K260 from the human protein were used as the immunogen for the CA2 antibody.
• Storage
  Prior to reconstitution, store at 4oC. After reconstitution, the CA2 antibody may be kept for up to one month refrigerated at +4 degrees C.For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
• Localization
  Cytoplasmic, nuclear
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  CA2   Carbonic   Anhydrase  
• Gene symbol
  CA2
• Short name
  Anti- CA2 / Carbonic Anhydrase II
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibodies to CA2 / Carbonic Anhydrase II
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:1373
• Gene
  CA2
• Long gene name
  carbonic anhydrase 2
• Synonyms gene name
  • carbonic anhydrase II
• Synonyms
  • Car2
  • CA-II
  • CAII
• GenBank acession
  • J03037
• Locus
  8q21.2
• Discovery year
  2001-06-22
• Entrez gene record
  760
• Pubmed identfication
  • 3107918
• RefSeq identity
  • NM_000067
• Classification
  • Carbonic anhydrases
• VEGA ID
  OTTHUMG00000164944

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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