BMP1 Antibody

• Catalog number
  F45359-0.08ML
• Price
  Please ask
• Size
  0.08 ml

• Category
  Antibody
• Concentration
  In 1X PBS, pH 7.4, with 0.09% sodium azide
• Form
  Purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  BMP1
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Mouse (Mus musculus) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  IHC, WB, ELISA
• Recommended dilutions
  IHC (Paraffin): 1:50-1:100,Western blot: 1:1000
• Notes
  Titration of the BMP1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This BMP1 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  P13497
• Purity
  Purified
• Description
  The BMP1 locus encodes a protein that is capable of inducing formation of cartilage in vivo. Although other bone morphogenetic proteins are members of the TGF-beta superfamily, BMP1 encodes a protein that is not closely related to other known growth factors. BMP1 protein and procollagen C proteinase (PCP), a secreted metalloprotease requiring calcium and needed for cartilage and bone formation, are identical. PCP or BMP1 protein cleaves the C-terminal propeptides of procollagen I, II, and III and its activity is increased by the procollagen C-endopeptidase enhancer protein. The BMP1 gene is expressed as alternatively spliced variants that share an N-terminal protease domain but differ in their C-terminal region.
• Immunogen
  A portion of amino acids 957-986 from the human protein was used as the immunogen for this BMP1 antibody.
• Storage
  Aliquot the BMP1 antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  BMP1  
• Gene symbol
  BMP1
• Short name
  Anti-BMP1
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit Ig
• Alternative name
  Antibodies to BMP1
• Alternative technique
  antibodies
• Alternative to gene target
  bone morphogenetic protein 1, OI13 and PCOLC and PCP and PCP2 and TLD, BMP1 and IDBG-10398 and ENSG00000168487 and 649, zinc ion binding, Extracellular, Bmp1 and IDBG-178672 and ENSMUSG00000022098 and 12153, BMP1 and IDBG-634694 and ENSBTAG00000000917 and

Gene info

• Identity
  HGNC:1067
• Gene
  BMP1
• Long gene name
  bone morphogenetic protein 1
• Synonyms gene
  • PCOLC
• Synonyms gene name
  • procollagen C-endopeptidase
• Synonyms
  • BMP-1
• Synonyms name
  • procollagen C-endopeptidase
  • tolloid-like
• Locus
  8p21.3
• Discovery year
  1990-06-11
• Entrez gene record
  649
• Pubmed identfication
  • 2004778
• RefSeq identity
  • NM_006132
• Classification
  • Bone morphogenetic proteins
  • Astacins
• VEGA ID
  OTTHUMG00000097761

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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