beta Defensin 1 Antibody

• Catalog number
  R30522
• Price
  Please ask
• Size
  0.1mg

• Category
  Antibody
• Concentration
  0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  beta Defensin 1
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, IHC-P
• Recommended dilutions
  Western blot: 0.5-1ug/ml,IHC (Paraffin): 0.5-1ug/ml
• Notes
  The stated application concentrations are suggested starting amounts. Titration of the beta Defensin 1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This beta Defensin 1 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  P60022
• Purity
  Antigen affinity
• Description
  Beta-defensin 1, is a protein that in humans is encoded by the DEFB1 gene. DEFB1 belongs to the defensin family. Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. The DEFB1 gene spans more than 7 kb and includes a large 6,962-bp intron. By 2-color fluorescence in situ hybridization on both metaphase chromosomes and released chromatin fiber, the DEFB1 gene is mapped to 8p23.2-p23.1, within 100 to 150 kb of the gene for human neutrophil defensin-alpha-1. DEFB1 may augment neonatal host defenses through antimicrobial effects or prime the adaptive immune system at mucosal surfaces.
• Immunogen
  An amino acid sequence from the C-terminus of human beta Defensin 1 (FTKIQGTCYRGKAKCCK) was used as the immunogen for this beta Defensin 1 antibody.
• Storage
  After reconstitution, the beta Defensin 1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Additional description
  human, mouse or other beta β- and alpha α- defensins are expressed by neutrophils ( α- ), lymphocytes and epithelial cells. DEFA DEFB genes defend the host against pathogens. GENTAUR supplies anti-defensins, monclonals, polyclonals antisera and recombinant DEFs or peptides of defensin.
• French translation
  anticorps

• Gene target
  beta   Defensin  
• Gene symbol
  DEFB1, DEFB108A, DEFB109A
• Short name
  Anti-beta Defensin 1
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibodies to beta Defensin 1
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:2766
• Gene
  DEFB1
• Long gene name
  defensin beta 1
• Synonyms gene name
  • defensin, beta 1
• Synonyms
  • HBD-1
  • DEFB-1
  • DEFB101
  • HBD1
  • BD1
  • MGC51822
• Synonyms name
  • beta-defensin 1
  • beta defensin 1
• GenBank acession
  • X92744
• Locus
  8p23.1
• Discovery year
  1997-05-29
• Entrez gene record
  1672
• Pubmed identfication
  • 7628632
• RefSeq identity
  • NM_005218
• Classification
  • Defensins, beta
• VEGA ID
  OTTHUMG00000090367

Gene info

• Identity
  HGNC:18089
• Gene
  DEFB108A
• Long gene name
  defensin beta 108A
• Synonyms gene
  • DEFB108
  • DEFB108P1
• Synonyms gene name
  • defensin, beta 108
  • defensin, beta 108, pseudogene 1
  • defensin beta 108 pseudogene 1
• Synonyms
  • DEFB-8
• Locus
  8p23.1
• Discovery year
  2002-05-09
• Entrez gene record
  503694
• Pubmed identfication
  • 11854508
• RefSeq identity
  • NG_005426
• Classification
  • Defensins, beta
• VEGA ID
  OTTHUMG00000165402

Gene info

• Identity
  HGNC:18090
• Gene
  DEFB109A
• Long gene name
  defensin beta 109A (pseudogene)
• Synonyms gene
  • DEFB109
  • DEFB109P1
• Synonyms gene name
  • defensin, beta 109
  • defensin, beta 109, pseudogene 1
  • defensin beta 109 pseudogene 1
• Synonyms
  • DEFB-9
• Locus
  8p23.1
• Discovery year
  2002-05-09
• Entrez gene record
  245912
• Pubmed identfication
  • 11854508
• RefSeq identity
  • NR_024044
• Classification
  • Defensins, beta
• VEGA ID
  OTTHUMG00000158671

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Similar products