Bcl10 Antibody
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Catalog numberR31853
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PricePlease ask
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Size0.1mg
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CategoryAntibody
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Concentration0.5mg/ml if reconstituted with 0.2ml sterile DI water
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FormAntigen affinity purified
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ConjugationUnconjugated
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ClonePolyclonal antibody
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Recognised antigenBcl10
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Host animalRabbit (Oryctolagus cuniculus)
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ClonalityPolyclonal (rabbit origin)
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Species reactivityHuman (Homo sapiens), Rat ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
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Tested applicationsWB
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Recommended dilutionsWestern blot: 0.1-0.5ug/ml
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NotesOptimal dilution of the Bcl10 antibody should be determined by the researcher.
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Intented useThis Bcl10 antibodyis to be used only for research purposes and not for diagnostics..
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UniprotO95999
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PurityAntigen affinity
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DescriptionBCL10, B-cell CLL/lymphoma 10, gene was identified by its translocation in a case of mucosa-associated lymphoid tissue (MALT) lymphoma. The BCL10 gene is mapped to chromosome 1p22. The protein encoded by this gene contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB. This protein is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regulators in NF-kappaB signaling. And this protein is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma. MALT1 and this protein are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy.
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ImmunogenAmino acids 1-233 of human Bcl10 were used as the immunogen for the Bcl10 antibody.
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StorageAfter reconstitution, the Bcl10 antibody may be kept for up to one month refrigerated at +4 degrees C.For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
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PropertiesIf you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolBCL10-AS1, BCL10, CARD11
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Short nameAnti-Bcl10
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TechniqueAntibody, antibodies against human proteins, antibodies for
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IsotypeRabbit IgG
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Alternative nameAntibodies to Bcl10
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Alternative techniqueantibodies
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Alternative to gene targetB-cell CLL/lymphoma 10, c-E10 and CARMEN and CIPER and CLAP and mE10, BCL10 and IDBG-100044 and ENSG00000142867 and 8915, NF-kappaB binding, nuclei, Bcl10 and IDBG-198751 and ENSMUSG00000028191 and 12042, BCL10 and IDBG-637289 and ENSBTAG00000013851 and 540824
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Gene info
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Identity
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Gene
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Long gene nameBCL10 antisense RNA 1
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Locus
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Discovery year2021-09-06
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Entrez gene record
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Classification
- Antisense RNAs
Gene info
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Identity
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Gene
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Long gene nameBCL10 immune signaling adaptor
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Synonyms gene name
- B cell CLL/lymphoma 10
- BCL10, immune signaling adaptor
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1999-01-08
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- CBM complex
- Caspase recruitment domain containing
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namecaspase recruitment domain family member 11
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Synonyms gene name
- caspase recruitment domain family, member 11
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2001-08-13
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Membrane associated guanylate kinases
- PDZ domain containing
- Caspase recruitment domain containing
- CBM complex
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data