BAG2 Antibody

• Catalog number
  R31211
• Price
  Please ask
• Size
  0.1mg

• Category
  Antibody
• Concentration
  0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  BAG2
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens), Mouse (Mus musculus), Rat ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB
• Recommended dilutions
  Western blot: 0.5-1ug/ml
• Notes
  The stated application concentrations are suggested starting amounts. Titration of the BAG2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This BAG2 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  O95816
• Purity
  Antigen affinity
• Description
  BAG family molecular chaperone regulator 2 is a protein that in humans is encoded by the BAG2 gene. The predicted protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All three proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. The functional antagonisms displayed between BAG family proteins and Hip suggest that a proper balance of these two types of protein is required for achieving optimal cycles of substrate binding and release required for inducting conformational changes in proteins, with Hip promoting peptide substrate binding by Hsc70/Hsp70 and BAG family proteins promoting dissociation.
• Immunogen
  An amino acid sequence from the N-terminus of human BAG family molecular chaperone regulator 2 (MAQAKINAKANEGR) was used as the immunogen for this BAG2 antibody.
• Storage
  After reconstitution, the BAG2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  BAG2  
• Gene symbol
  BAG2
• Short name
  Anti-BAG2
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibodies to BAG2
• Alternative technique
  antibodies
• Alternative to gene target
  BCL2-associated athanogene 2, BAG-2 and dJ417I1.2, BAG2 and IDBG-91571 and ENSG00000112208 and 9532, chaperone binding, multiple, Bag2 and IDBG-140714 and ENSMUSG00000042215 and 213539, BAG2 and IDBG-628617 and ENSBTAG00000005355 and 506107

Gene info

• Identity
  HGNC:938
• Gene
  BAG2
• Long gene name
  BAG cochaperone 2
• Synonyms gene name
  • BCL2 associated athanogene 2
• GenBank acession
  • AF095192
• Locus
  6p12.1
• Discovery year
  1999-04-23
• Entrez gene record
  9532
• Pubmed identfication
  • 9873016
• Classification
  • BAG cochaperones
• VEGA ID
  OTTHUMG00000014919

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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