Aurka Antibody

• Catalog number
  F44002-0.4ML
• Price
  Please ask
• Size
  0.4 ml

• Category
  Antibody
• Concentration
  In 1X PBS, pH 7.4, with 0.09% sodium azide
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  Aurka
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Mouse (Mus musculus) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, ELISA
• Recommended dilutions
  Western blot: 1:1000
• Notes
  Titration of the Aurka antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This Aurka antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  P97477
• Purity
  Antigen affinity
• Description
  Contributes to the regulation of cell cycle progression. Required for normal mitosis. Associates with the centrosome and the spindle microtubules during mitosis and functions in centrosome maturation, spindle assembly, maintenance of spindle bipolarity, centrosome separation and mitotic checkpoint control. Phosphorylates numerous target proteins, including ARHGEF2, BRCA1, KIF2A, NDEL1, PARD3, PLK1 and BORA. Regulates KIF2A tubulin depolymerase activity (By similarity). Required for normal axon formation. Plays a role in microtubule remodeling during neurite extension. Important for microtubule formation and/or stabilization.
• Immunogen
  A portion of amino acids 93-120 from the mouse protein was used as the immunogen for this Aurka antibody.
• Storage
  Aliquot the Aurka antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Aurka  
• Gene symbol
  AURKA
• Short name
  Anti-Aurka
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit Ig
• Alternative name
  Antibodies to Aurka
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:11393
• Gene
  AURKA
• Long gene name
  aurora kinase A
• Synonyms gene
  • STK15
  • STK6
• Synonyms gene name
  • serine/threonine kinase 15
  • serine/threonine kinase 6
• Synonyms
  • BTAK
  • AurA
  • STK7
  • ARK1
  • PPP1R47
  • AIK
• Synonyms name
  • protein phosphatase 1, regulatory subunit 47
  • Aurora-A kinase
• GenBank acession
  • BC001280
• Locus
  20q13.2
• Discovery year
  1998-10-02
• Entrez gene record
  6790
• Pubmed identfication
  • 9174055
  • 9771714
• RefSeq identity
  • NM_003600
• Classification
  • Protein phosphatase 1 regulatory subunits
• VEGA ID
  OTTHUMG00000032796

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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