ATF6 beta Antibody
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Catalog numberF49022-0.08ML
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PricePlease ask
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Size0.08 ml
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CategoryAntibody
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ConcentrationIn 1X PBS pH 7.4 with 0.09% sodium azide
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FormAntigen affinity purified
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ConjugationUnconjugated
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ClonePolyclonal antibody
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Recognised antigenATF6 beta
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Host animalRabbit (Oryctolagus cuniculus)
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ClonalityPolyclonal (rabbit origin)
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Species reactivityHuman (Homo sapiens), Hamster, Mouse (Mus musculus) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
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Tested applicationsIHC, WB, ELISA
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Recommended dilutionsIHC (Paraffin): 1:25,Western blot: 1:1000
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NotesTitration of the ATF6 beta antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Intented useThis ATF6 beta antibodyis to be used only for research purposes and not for diagnostics..
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UniprotQ99941
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PurityAntigen affinity
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DescriptionATF6 beta is a transcription factor in the unfolded protein response (UPR) pathway during ER stress. Either as a homodimer or as a heterodimer with ATF6-alpha, the encoded protein binds to the ER stress response element, interacting with nuclear transcription factor Y to activate UPR target genes. The protein is normally found in the membrane of the endoplasmic reticulum; however, under ER stress, the N-terminal cytoplasmic domain is cleaved from the rest of the protein and translocates to the nucleus.
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ImmunogenA portion of amino acids 560-589 from the human protein was used as the immunogen for this ATF6 beta antibody.
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StorageAliquot the ATF6 beta antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
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PropertiesIf you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolATF6, ATF6-DT
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Short nameAnti-ATF6 beta
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TechniqueAntibody, antibodies against human proteins, antibodies for
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IsotypeRabbit Ig
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Alternative nameAntibodies to ATF6 beta
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameactivating transcription factor 6
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1999-12-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Basic leucine zipper proteins
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameATF6 divergent transcript
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Locus
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Discovery year2021-08-02
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Entrez gene record
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Classification
- Divergent transcripts
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data