AQP5 Antibody Aquaporin 5

• Catalog number
  R30630
• Price
  Please ask
• Size
  0.1mg

• Category
  Antibody
• Concentration
  0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  AQP5 Aquaporin 5
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB
• Recommended dilutions
  Western blot: 0.5-1ug/ml
• Notes
  The stated application concentrations are suggested starting amounts. Titration of the AQP5 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This AQP5 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  P55064
• Purity
  Antigen affinity
• Description
  Aquaporin 5 is a water channel protein. The aquaporins (AQPs) are a family of more than 10 homologous water transporting proteins expressed in many mammalian epithelia and endothelia. At least five AQPs are expressed in the eye: AQP0/MIP in lens fiber, AQP1 in cornea endothelium, ciliary and lens epithelia and trabecular meshwork, AQP3 in conjunctiva, AQP4 in ciliary epithelium and retinal Müller cells, and AQP5 in corneal and lacrimal gland epithelia. Among the seven human aquaporins cloned to date (AQPs 0-6), genes encoding the four most closely related aquaporins (AQP0, -2, -5, and -6) have been mapped to chromosome band 12q13, suggesting an aquaporin family gene cluster at this locus. AQP5 plays a role in the generation of saliva, tears and pulmonary secretions.
• Immunogen
  An amino acid sequence from the C-terminus of human Aquaporin 5 (DEDWEEQREERKKTMELTTR) was used as the immunogen for this AQP5 antibody.
• Storage
  After reconstitution, the AQP5 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  AQP5   Aquaporin  
• Gene symbol
  AQP5, AQP5-AS1
• Short name
  Anti-AQP5 Aquaporin 5
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibodies to AQP5 Aquaporin 5
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:638
• Gene
  AQP5
• Long gene name
  aquaporin 5
• GenBank acession
  • U46569
• Locus
  12q13.12
• Discovery year
  1994-07-25
• Entrez gene record
  362
• Pubmed identfication
  • 8621489
  • 23830519
• RefSeq identity
  • NM_001651
• Classification
  • Aquaporins
• VEGA ID
  OTTHUMG00000169710

Gene info

• Identity
  HGNC:55474
• Gene
  AQP5-AS1
• Long gene name
  AQP5 and AQP2 antisense RNA 2
• Locus
  12q13.12
• Discovery year
  2021-03-11
• Entrez gene record
  101927318
• RefSeq identity
  • NR_110590
• Classification
  • Antisense RNAs

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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