AP2 alpha Antibody (TFAP2A, Activator protein 2)

• Catalog number
  F47550-0.08ML
• Price
  Please ask
• Size
  0.08 ml

• Category
  Antibody
• Concentration
  In 1X PBS, pH 7.4, with 0.09% sodium azide
• Form
  Purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  AP2 alpha (TFAP2A, Activator protein 2)
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, ELISA
• Recommended dilutions
  Western blot: 1:1000
• Notes
  Titration of the AP2 alpha antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This AP2 alpha antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  P05549
• Purity
  Purified
• Description
  Activator protein 2 alpha is expressed in neural crest cell lineages with the highest levels of expression corresponding to early neural crest cells, suggesting that TFAP2A plays a role in their differentiation and development. TFAP2A is expressed in ectoderm and in neural-crest cells migrating from the cranial folds during closure of the neural tube in the mouse. Cranial neural crest cell provides patterning information for craniofacial morphogenesis and generate most of the skull bones and the cranial ganglia.
• Immunogen
  A portion of amino acids 407-436 from the human protein was used as the immunogen for this AP2 alpha antibody.
• Storage
  Aliquot the AP2 alpha antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
• Additional description
  The Anti-AP2 alpha (TFAP2A, Activator protein 2) is a α- or alpha protein sometimes glycoprotein present in blood.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  AP2   alpha   TFAP2A   Activator   protein  
• Gene symbol
  TFAP2A-AS1, GTF3A, TFAP2A-AS2, FABP4, TFAP2B, TFAP2C, TFAP2A
• Short name
  Anti-AP2 alpha (TFAP2A, Activator protein 2)
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit Ig
• Alternative name
  Antibodies to AP2 alpha (TFAP2A, Activator protein 2)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:40579
• Gene
  TFAP2A-AS1
• Long gene name
  TFAP2A antisense RNA 1
• Locus
  6p24.3
• Discovery year
  2013-07-24
• Entrez gene record
  100130275
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000014233

Gene info

• Identity
  HGNC:4662
• Gene
  GTF3A
• Long gene name
  general transcription factor IIIA
• Synonyms
  • TFIIIA
  • AP2
• Locus
  13q12.2
• Discovery year
  1994-12-22
• Entrez gene record
  2971
• Pubmed identfication
  • 7789179
• RefSeq identity
  • NM_002097
• Classification
  • General transcription factors
  • Zinc fingers C2H2-type
• VEGA ID
  OTTHUMG00000016632

Gene info

• Identity
  HGNC:52289
• Gene
  TFAP2A-AS2
• Long gene name
  TFAP2A antisense RNA 2
• Synonyms
  • HIPSTR
• Synonyms name
  • heterogeneously expressed from the Intronic Plus Strand of the TFAP2A-locus RNA
• GenBank acession
  • LF209760
• Locus
  6p24.3
• Discovery year
  2017-02-15
• Pubmed identfication
  • 27605307
• Classification
  • Antisense RNAs

Gene info

• Identity
  HGNC:3559
• Gene
  FABP4
• Long gene name
  fatty acid binding protein 4
• Synonyms
  • A-FABP
  • aP2
• Synonyms name
  • adipocyte fatty acid binding protein
• GenBank acession
  • J02874
• Locus
  8q21.13
• Discovery year
  1991-08-06
• Entrez gene record
  2167
• Pubmed identfication
  • 2481498
• RefSeq identity
  • NM_001442
• Classification
  • Fatty acid binding protein family
• VEGA ID
  OTTHUMG00000164602

Gene info

• Identity
  HGNC:11743
• Gene
  TFAP2B
• Long gene name
  transcription factor AP-2 beta
• Synonyms gene name
  • transcription factor AP-2 beta (activating enhancer-binding protein 2 beta)
  • transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
• Synonyms
  • AP2-B
  • AP-2beta
• GenBank acession
  • X95694
• Locus
  6p12.3
• Discovery year
  1995-12-18
• Entrez gene record
  7021
• Pubmed identfication
  • 7555706
  • 8661133
• RefSeq identity
  • NM_003221
• Classification
  • Transcription factor AP-2 family
• VEGA ID
  OTTHUMG00000014836

Gene info

• Identity
  HGNC:11744
• Gene
  TFAP2C
• Long gene name
  transcription factor AP-2 gamma
• Synonyms gene name
  • transcription factor AP-2 gamma (activating enhancer-binding protein 2 gamma)
• Synonyms
  • AP2-GAMMA
  • ERF1
  • TFAP2G
  • hAP-2g
• Synonyms name
  • estrogen receptor factor 1
• Locus
  20q13.31
• Discovery year
  1997-01-08
• Entrez gene record
  7022
• Pubmed identfication
  • 8661133
• RefSeq identity
  • NM_003222
• Classification
  • Transcription factor AP-2 family
• VEGA ID
  OTTHUMG00000032805

Gene info

• Identity
  HGNC:11742
• Gene
  TFAP2A
• Long gene name
  transcription factor AP-2 alpha
• Synonyms gene
  • TFAP2
  • AP2TF
• Synonyms gene name
  • transcription factor AP-2 alpha (activating enhancer-binding protein 2 alpha)
  • transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
• Synonyms
  • AP-2
  • AP-2alpha
• GenBank acession
  • X52611
• Locus
  6p24.3
• Discovery year
  1991-09-12
• Entrez gene record
  7020
• Pubmed identfication
  • 1916817
  • 3063603
• RefSeq identity
  • NM_003220
• Classification
  • Transcription factor AP-2 family
• VEGA ID
  OTTHUMG00000014235

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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