Alpha 1 Antitrypsin Antibody

• Catalog number
  R31767
• Price
  Please ask
• Size
  0.1mg

• Category
  Antibody
• Concentration
  0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  Alpha 1 Antitrypsin
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Mouse (Mus musculus), Rat ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, IHC-P
• Recommended dilutions
  Western blot: 0.5-1ug/ml,IHC (Paraffin): 0.5-1ug/ml
• Notes
  The stated application concentrations are suggested starting amounts. Titration of the Alpha 1 Antitrypsin antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This Alpha 1 Antitrypsin antibodyis to be used only for research purposes and not for diagnostics..
• Gene ID
  24648
• Purity
  Antigen affinity
• Description
  Alpha 1 Antitrypsin is secreted serine protease inhibitor whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Defects in this gene can cause emphysema or liver disease. Several transcript variants encoding the same protein have been found for this SERPINA1 gene.
• Immunogen
  Rat partial recombinant protein (AA 211-411) was used as the immunogen for this Alpha 1 Antitrypsin antibody.
• Storage
  After reconstitution, the Alpha 1 Antitrypsin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
• Additional description
  The Anti-Alpha 1 Antitrypsin is a α- or alpha protein sometimes glycoprotein present in blood.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Alpha   Antitrypsin  
• Gene symbol
  SERPINA1, SERPINA2, SERPINA7
• Short name
  Anti-Alpha 1 Antitrypsin
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibodies to Alpha 1 Antitrypsin
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:8941
• Gene
  SERPINA1
• Long gene name
  serpin family A member 1
• Synonyms gene
  • PI
• Synonyms gene name
  • serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
  • serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
• Synonyms
  • AAT
  • A1A
  • PI1
  • alpha-1-antitrypsin
  • A1AT
  • alpha1AT
• Synonyms name
  • protease inhibitor 1
  • anti-elastase
  • alpha-1 antitrypsin
  • alpha-1 proteinase inhibitor
• GenBank acession
  • X01683
• Locus
  14q32.13
• Discovery year
  1986-01-01
• Entrez gene record
  5265
• Pubmed identfication
  • 24172014
• RefSeq identity
  • NM_001002235
• Classification
  • Serpin peptidase inhibitors
• VEGA ID
  OTTHUMG00000150355
• Locus Specific Databases
  • LRG_575

Gene info

• Identity
  HGNC:8985
• Gene
  SERPINA2
• Long gene name
  serpin family A member 2 (gene/pseudogene)
• Synonyms gene
  • PIL
  • SERPINA2P
• Synonyms gene name
  • serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 2
  • serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 2, pseudogene
  • serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 2 (gene/pseudogene)
• Synonyms
  • ATR
  • ARGS
• Synonyms name
  • protease inhibitor 1 (alpha-1-antitrypsin)-like
  • alpha-1 antitrypsin-related protein
• GenBank acession
  • JX680599
• Locus
  14q32.13
• Discovery year
  2001-06-22
• Entrez gene record
  390502
• Pubmed identfication
  • 15014966
  • 23826168
  • 24172014
• RefSeq identity
  • NM_006220
• Classification
  • Serpin peptidase inhibitors
• VEGA ID
  OTTHUMG00000171347

Gene info

• Identity
  HGNC:11583
• Gene
  SERPINA7
• Long gene name
  serpin family A member 7
• Synonyms gene
  • TBG
• Synonyms gene name
  • serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
  • serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
• Synonyms name
  • thyroxin-binding globulin
  • thyroxine-binding globulin
  • alpha-1 antiproteinase, antitrypsin
• GenBank acession
  • M14091
• Locus
  Xq22.3
• Discovery year
  1986-01-01
• Entrez gene record
  6906
• Pubmed identfication
  • 24172014
• RefSeq identity
  • NM_000354
• Classification
  • Serpin peptidase inhibitors
• VEGA ID
  OTTHUMG00000022144
• Locus Specific Databases
  • Global Variome shared LOVD

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Similar products