ADRB2 Antibody

• Catalog number
  R31906
• Price
  Please ask
• Size
  0.1mg

• Category
  Antibody
• Concentration
  0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  ADRB2
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens), Rat ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB
• Recommended dilutions
  Western blot: 0.1-0.5ug/ml
• Notes
  Optimal dilution of the ADRB2 antibody should be determined by the researcher.
• Intented use
  This ADRB2 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  P07550
• Purity
  Antigen affinity
• Description
  ADRB2, also known as beta-2 adrenergic receptor, is a beta-adrenergic receptor within a cell membrane which reacts with adrenaline (epinephrine) as a hormone or neurotransmitter affecting muscles or organs. It is mapped to 5q32. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. The genetic variation in the ADRB2 gene may be of major importance for obesity, energy expenditure, and lipolytic ADRB2 function in adipose tissue, at least in women. What’s more, it has been found that activation of ADRB2 receptors can stimulate gamma-secretase activity and beta-amyloid production, and the ADRB2 receptors activator may contribute to beta-amyloid accumulation in AD.
• Immunogen
  Amino acids RVFQEAKRQLQKIDKSEGRFHVQNLSQVEQDGRTGH of human ADRB2 were used as the immunogen for the ADRB2 antibody.
• Storage
  After reconstitution, the ADRB2 antibody may be kept for up to one month refrigerated at +4 degrees C.For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  ADRB2  
• Gene symbol
  ADRB2
• Short name
  Anti-ADRB2
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibodies to ADRB2
• Alternative technique
  antibodies
• Alternative to gene target
  adrenoceptor beta 2, surface, ADRB2R and ADRBR and B2AR and BAR and BETA2AR, ADRB2 and IDBG-52685 and ENSG00000169252 and 154, norepinephrine binding, nuclei, Adrb2 and IDBG-152615 and ENSMUSG00000045730 and 11555, ADRB2 and IDBG-648668 and ENSBTAG00000002144 and 281605

Gene info

• Identity
  HGNC:286
• Gene
  ADRB2
• Long gene name
  adrenoceptor beta 2
• Synonyms gene
  • ADRB2R
• Synonyms gene name
  • adrenergic, beta-2-, receptor, surface
  • adrenoceptor beta 2, surface
• Synonyms
  • ADRBR
  • BAR
  • B2AR
• GenBank acession
  • AF022953
• Locus
  5q32
• Discovery year
  1990-09-10
• Entrez gene record
  154
• RefSeq identity
  • NM_000024
• Classification
  • Adrenoceptors
• VEGA ID
  OTTHUMG00000129933

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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