ADAMTS13 Antibody

• Catalog number
  R32496
• Price
  Please ask
• Size
  0.1mg

• Category
  Antibody
• Concentration
  0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  ADAMTS13
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens), Mouse (Mus musculus), Rat ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, ELISA (protein)
• Recommended dilutions
  Western blot: 0.5-1ug/ml,ELISA: 0.5-1ug/ml (human protein tested); request BSA-free format for coating
• Added buffer
  Lyophilized from 1X Phosphate Buffered Saline (PBS) with 2.5% BSA and 0.025% sodium azide
• Intented use
  This ADAMTS13 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  Q76LX8
• Purity
  Antigen affinity
• Description
  ADAMTS13 (A disintegrin and metalloproteinase with athrombospondin type 1 motif, member 13), also known as VWFCP, is a zinc-containing metalloprotease enzyme that cleaves von Willebrand factor (vWf), a large protein involved in blood clotting. It is secreted in blood and degrades large vWf multimers, decreasing their activity. This gene encodes a member of a family of proteins containing several distinct regions, including a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. This gene is mapped to 9q34.
• Immunogen
  Amino acids A299-R488 from the human protein were used as the immunogen for the ADAMTS13 antibody.
• Storage
  After reconstitution, the ADAMTS13 antibody may be kept for up to one month refrigerated at +4 degrees C.For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
• Localization
  Cytoplasmic
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  ADAMTS13  
• Gene symbol
  ADAMTS13
• Short name
  Anti- ADAMTS13
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibodies to ADAMTS13
• Alternative technique
  antibodies
• Alternative to gene target
  ADAM metallopeptidase with thrombospondin type 1 motif, 13, ADAM-TS13 and ADAMTS-13 and C9orf8 and vWF-CP and VWFCP, ADAMTS13 and IDBG-91330 and ENSG00000160323 and 11093, zinc ion binding, Extracellular, Adamts13 and IDBG-150457 and ENSMUSG00000014852 and 279028, ADAMTS13 and IDBG-640733 and ENSBTAG00000015093 and

Gene info

• Identity
  HGNC:1366
• Gene
  ADAMTS13
• Long gene name
  ADAM metallopeptidase with thrombospondin type 1 motif 13
• Synonyms gene
  • C9orf8
• Synonyms gene name
  • a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 13
• Synonyms
  • VWFCP
  • TTP
  • vWF-CP
  • FLJ42993
  • MGC118899
  • MGC118900
  • DKFZp434C2322
• GenBank acession
  • AJ011374
• Locus
  9q34.2
• Discovery year
  1999-08-23
• Entrez gene record
  11093
• Pubmed identfication
  • 11557746
  • 11535495
• RefSeq identity
  • NM_139025
• Classification
  • ADAM metallopeptidases with thrombospondin type 1 motif
• VEGA ID
  OTTHUMG00000020876
• Locus Specific Databases
  • LRG_544

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Similar products